Evidence of Bacterial Biofilms on Frontal Recess Stents in Patients with Chronic Rhinosinusitis

Perloff, Joel R.; Palmer, James N.

doi:10.1177/194589240401800607

Cited by 105 publications

(90 citation statements)

References 11 publications

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“…1308 Silastic stents have been associated with biofilm formation postoperatively, which maybe counterproductive in the treatment of CRS. 1310 In an "off-label" use, nonbiodegradable spacers such as the Relieva Stratus Microflow Spacer TM (Acclarent, Irvine, CA) have been used as an drug-eluting stent by filling the spacer with triamcinolone. 1308,1311 However, these can be difficult to remove, with a case report of retained spacers leading to inflammation and infection 7 months after initial insertion.…”

Section: Xd6 Surgical Principles/techniques: Drug Eluting Packingmentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

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559

888

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Background:The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods:Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results:The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AE-CRS), and pediatric RS. Conclusion:As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too o en the foundation upon which these recommendations are based is comprised of lowerlevel evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed. C 2016 ARS-AAOA, LLC. Key Words:rhinosinusitis; chronic rhinosinusitis; acute rhinosinusitis; recurrent acute rhinosinusitis; evidence-based medicine; systematic review; endoscopic sinus surgery List of Abbreviations Used

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Section: Xd6 Surgical Principles/techniques: Drug Eluting Packingmentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

Self Cite

559

888

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“…This group of infectious diseases includes chronic tonsillitis, adenoiditis, CRS with or without nasal polyposis, chronic otitis media, periodontitis, chronic prostatitis, and chronic pelvic inXammatory disease [7][8][9][10]. Furthermore, presence of bioWlms could be a great therapeutic problem on the surface of diVerent surgical implants, which might be responsible for antibiotic-and antimycotic-resistant postoperative infections [11]. Bacterial-and fungal colonies exist as free planktonic prokaryote-or eukaryote cells or as complex bioWlm webs [2,7].…”

mentioning

confidence: 99%

Optical coherence tomography for biofilm detection in chronic rhinosinusitis with nasal polyposis

Tóth

Vajas

Csomor

et al. 2012

Eur Arch Otorhinolaryngol

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“…Currently fluorescent in situ hybridization (FISH)/ confocal laser scanning microscopy (CLSM) is accepted as a gold standart for detection of biofilms, due to nondestructive trait and using species-specific oligonucleotide probes (17,18). Foreman et al (19) recently revealed BacLight/CSLM, possessing an equivalent sensitivity of FISH/ CSLM, by analyzing sinus mucosal tissues from 20 CRS patients.…”

Section: Detection Of Biofilmmentioning

confidence: 99%

Biofilms in Otolaryngology

Develioğlu¹,

Külekçi²

2013

JAREM

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Biofilms have been shown to play an important role in otolaryngologic disorders. Recent advances have demonstrated that there are different bacterial species within the biofilms in different disease states. Since the recognition that chronic otolaryngologic infections are associated with biofilms, new treatment strategies with new agents have been trying to be developed for antibiotic-resistant bacterial biofilms. It has been well known that inadequate doses of antibiotic treatment can trigger biofilm formation and can lead to chronic infections. In fact, to diagnose, treat and prevent biofilm-related illnesses, different strategies are required. Determining the bacterial genetics of biofilm formation and the interaction between host and bacteria will provide substantial targets for biofilm drug therapies. The main goal of this review is to evaluate and discuss in detail some of the recent findings in biofilms-related otolaryngologic states. (JAREM 2013; 3: 1-4) Key Words: Biofilm, otolaryngology ÖZETBiofilmlerin otolarengolojik hastalıklarda önemli bir rolü olduğu gösterilmiştir. Yakın zamanda yapılan çalışmalarda farklı hastalık durumlarında biofilmlerin içinde farklı mikroorganizma türlerinin bulunduğu saptanmıştır. Kronik otolarengolojik infeksiyonların biofilmler ile ilişkili olduğu anlaşıldıktan sonra, özellikle antibiyotiklere dirençli olduğu bilinen bakteriyel biofilmler için yeni ajanları içeren tedavi stratejilerinin geliştirilmesine çalışılmaktadır. Uygun olmayan dozlarda antibiyotik tedavisi biofilm oluşumunu ve kronik enfeksiyonların gelişimini tetikleyebilir. Biofilmler ile ilişkili hastalıkların tanısı, tedavisi ve önlenmesi için farklı stratejilere gereksinim vardır. Biofilm oluşumunun bakteriyel genetik alt yapısının saptanması ve konak ile bakteri arasındaki etkileşimin anlaşılması, biofilme bağlı enfeksiyonların tedavisi için doğru hedeflerin belirlenmesini sağlayacaktır. Bu derlemenin esas amacı biofilm ile ilişkili otolarengolojik hastalıklardaki yeni gelişmelerin detaylı bir şekilde tartışılarak değerlendirilmesidir. (JAREM 2013; 3: 1-4) Anahtar Sözcükler: Biofilm, otolarengoloji

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Evidence of Bacterial Biofilms on Frontal Recess Stents in Patients with Chronic Rhinosinusitis

Abstract: This is evidence of the possible presence of bacterial biofilms on frontal sinus stents in patients with chronic sinusitis. Further study into the role of bacterial biofilms in perpetuating chronic sinusitis is warranted.

Cited by 105 publications

References 11 publications

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Optical coherence tomography for biofilm detection in chronic rhinosinusitis with nasal polyposis

Biofilms in Otolaryngology

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