The murder case of a female pulmonologist in Nabire, Central Papua, in March 2023 was used as a research study because it was a special case. Because at that time, investigators had difficulty determining the suspect because of the lack of evidence at the beginning of the investigation. This study aims to obtain a description of the Scientific Investigation Technique in disclosing the crime of murder by using a qualitative approach, while the research method is the case study method. The research was conducted at the Nabire Police Criminal Investigation Unit to find out the steps of the Nabire Police Criminal Investigation Unit in using Scientific Investigation through DNA. This study shows that the Scientific investigation method used by the Barelang Police Criminal Investigation Unit has assisted in disclosing the crime of murder effectively with supporting and inhibiting factors.