Evolution of extraction technique for the separation of bioactive compounds from <i>Aegle marmelos</i>

Srivastava, Rashi; Parambil, Jose V.

doi:10.1080/01496395.2022.2151470

Cited by 2 publications

(1 citation statement)

References 85 publications

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“…Non-bioassay-guided purification is cost-effective, but there are risks of losing bioactive agents during purification, particularly those minor compounds. Thus, selecting a suitable method is crucial to obtain maximum target compounds [ 148 ].…”

Section: Approaches and Techniques For The Biodiscovery Of Anti-infla...mentioning

confidence: 99%

Approaches, Strategies and Procedures for Identifying Anti-Inflammatory Drug Lead Molecules from Natural Products

Jamtsho,

Yeshi,

Perry

et al. 2024

Pharmaceuticals

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Natural products (NPs) have played a vital role in human survival for millennia, particularly for their medicinal properties. Many traditional medicine practices continue to utilise crude plants and animal products for treating various diseases, including inflammation. In contrast, contemporary medicine focuses more on isolating drug-lead compounds from NPs to develop new and better treatment drugs for treating inflammatory disorders such as inflammatory bowel diseases. There is an ongoing search for new drug leads as there is still no cure for many inflammatory conditions. Various approaches and technologies are used in drug discoveries from NPs. This review comprehensively focuses on anti-inflammatory small molecules and describes the key strategies in identifying, extracting, fractionating and isolating small-molecule drug leads. This review also discusses the (i) most used approaches and recently available techniques, including artificial intelligence (AI), (ii) machine learning, and computational approaches in drug discovery; (iii) provides various animal models and cell lines used in in-vitro and in-vivo assessment of the anti-inflammatory potential of NPs.

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Section: Approaches and Techniques For The Biodiscovery Of Anti-infla...mentioning

confidence: 99%

Approaches, Strategies and Procedures for Identifying Anti-Inflammatory Drug Lead Molecules from Natural Products

Jamtsho,

Yeshi,

Perry

et al. 2024

Pharmaceuticals

View full text Add to dashboard Cite

show abstract

Three decades of advances in extraction and analytical techniques for guava (Psidium guajava L.): A review

Bylappa,

Balasubramanian,

Park

et al. 2024

Results in Chemistry

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Evolution of extraction technique for the separation of bioactive compounds from Aegle marmelos

Cited by 2 publications

References 85 publications

Approaches, Strategies and Procedures for Identifying Anti-Inflammatory Drug Lead Molecules from Natural Products

Approaches, Strategies and Procedures for Identifying Anti-Inflammatory Drug Lead Molecules from Natural Products

Three decades of advances in extraction and analytical techniques for guava (Psidium guajava L.): A review

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