“…48]. Osteitis fibrosa may worsen, persist or improve in patients un dergoing CAPD, largely depending on calcium balance [45,48,50,51,54]. In a comparative study of hemodial ysis and CAPD patients who were adequately supple mented with calcium and vitamin D, improvement in osteitis fibrosa was comparable in each group, and osteo malacia was more responsive to CAPD treatment [57], Treatment with CAPD caused shortening of mineraliza tion time which was attributed to enhanced mineraliza tion capacity of the osteoblasts, independently of the patient's aluminum status [58], Those patients with a large amount of nonmineralized bone matrix responded to CAPD with a reduction in relative osteoid volume, mean osteoid seam width and total osteoid surface.…”