Evolution of root-specific carotenoid precursor pathways for apocarotenoid signal biogenesis

Walter, Michael H.; Stauder, Ron; Tissier, Alain

doi:10.1016/j.plantsci.2014.12.017

Cited by 42 publications

(25 citation statements)

References 80 publications

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“…ASV2 lacks this hairpin and is translation-permissive. Interestingly, in most plant taxa, PSY constitutes a small three-member gene family, while in Brassicaceae there is only one PSY gene (Walter et al, 2015). This sophisticated mechanism of duplication of gene function is probably a means that Brassicaceae have evolved to perform multiple activities (which in other species require several genes) with only one gene copy.…”

Section: Translation Regulation Mediated By Structural Features Of Thmentioning

confidence: 99%

Translation regulation in plants: an interesting past, an exciting present and a promising future

2017

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SUMMARYChanges in gene expression are at the core of most biological processes, from cell differentiation to organ development, including the adaptation of the whole organism to the ever-changing environment. Although the central role of transcriptional regulation is solidly established and the general mechanisms involved in this type of regulation are relatively well understood, it is clear that regulation at a translational level also plays an essential role in modulating gene expression. Despite the large number of examples illustrating the critical role played by translational regulation in determining the expression levels of a gene, our understanding of the molecular mechanisms behind such types of regulation has been slow to emerge. With the recent development of high-throughput approaches to map and quantify different critical parameters affecting translation, such as RNA structure, protein-RNA interactions and ribosome occupancy at the genome level, a renewed enthusiasm toward studying translation regulation is warranted. The use of these new powerful technologies in well-established and uncharacterized translation-dependent processes holds the promise to decipher the likely complex and diverse, but also fascinating, mechanisms behind the regulation of translation.

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Section: Translation Regulation Mediated By Structural Features Of Thmentioning

confidence: 99%

Translation regulation in plants: an interesting past, an exciting present and a promising future

2017

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“…These compounds play crucial roles in plant-environment crosstalk, e.g. attraction of pollinators, herbivore deterrence and defense against pathogen (Walter, Stauder, & Tissier, 2015). This epigenetic mechanism is mediated by a chromatin-modifying histone methyltransferase enzyme (carotenoid chloroplast regulatory1, CCR1 or set domain group 8, SDG8) required for CRTISO expression (Cazzonelli et al, 2009).…”

Section: Biosynthesis Of Carotenoids In Plantsmentioning

confidence: 99%

Carotenoids from fruits and vegetables: Chemistry, analysis, occurrence, bioavailability and biological activities

Saini

Nile

Park

2015

Food Research International

620

313

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“…In fact, pathway flux control though PSY is required, e.g. during abiotic stress for increased ABA formation (Li et al, 2008;Welsch et al, 2008;Arango et al, 2010), upon mycorrhization (Walter et al, 2015) and during deetiolation (von Lintig et al, 1997;Welsch et al, 2000;Rodríguez-Villalón et al, 2009).…”

Section: Compensation Of the Single-gene Situation By Alternative Tramentioning

confidence: 99%

“…Seemingly, in most taxa, there is a work-sharing as witnessed by the fact that PSY constitutes a small gene family of generally three members showing differential transcriptional regulation (Walter et al, 2015). In contrast, Arabidopsis and most other Brassicaceae have only one single PSY gene (Arabidopsis Genome Initiative, 2000).…”

mentioning

confidence: 99%

Carotenogenesis Is Regulated by 5′UTR-Mediated Translation of Phytoene Synthase Splice Variants

et al. 2016

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Phytoene synthase (PSY) catalyzes the highly regulated, frequently rate-limiting synthesis of the first biosynthetically formed carotene. While PSY constitutes a small gene family in most plant taxa, the Brassicaceae, including Arabidopsis (Arabidopsis thaliana), predominantly possess a single PSY gene. This monogenic situation is compensated by the differential expression of two alternative splice variants (ASV), which differ in length and in the exon/intron retention of their 59UTRs. ASV1 contains a long 59UTR (untranslated region) and is involved in developmentally regulated carotenoid formation, such as during deetiolation. ASV2 contains a short 59UTR and is preferentially induced when an immediate increase in the carotenoid pathway flux is required, such as under salt stress or upon sudden light intensity changes. We show that the long 59UTR of ASV1 is capable of attenuating the translational activity in response to high carotenoid pathway fluxes. This function resides in a defined 59UTR stretch with two predicted interconvertible RNA conformations, as known from riboswitches, which might act as a flux sensor. The translation-inhibitory structure is absent from the short 59UTR of ASV2 allowing to bypass translational inhibition under conditions requiring rapidly increased pathway fluxes. The mechanism is not found in the rice (Oryza sativa) PSY1 59UTR, consistent with the prevalence of transcriptional control mechanisms in taxa with multiple PSY genes. The translational control mechanism identified is interpreted in terms of flux adjustments needed in response to retrograde signals stemming from intermediates of the plastid-localized carotenoid biosynthesis pathway.

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Evolution of root-specific carotenoid precursor pathways for apocarotenoid signal biogenesis

Cited by 42 publications

References 80 publications

Translation regulation in plants: an interesting past, an exciting present and a promising future

Translation regulation in plants: an interesting past, an exciting present and a promising future

Carotenoids from fruits and vegetables: Chemistry, analysis, occurrence, bioavailability and biological activities

Carotenogenesis Is Regulated by 5′UTR-Mediated Translation of Phytoene Synthase Splice Variants

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