2024
DOI: 10.1101/2024.07.14.603414
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Evolutionary Dynamics of Lineage-Specific Class-A GPCR Subsets Reveal Widespread Chemosensory Roles and Adaptations in Lophotrochozoa

Rohan Nath,
Biswajit Panda,
Rakesh Siuli
et al.

Abstract: Detecting external chemosensory cues via Class-A G protein-coupled receptors (GPCRs) is essential for behavioral and biological functions, influencing animal evolution and ecological adaptations. While well-studied in vertebrates and echinoderms, their role in major clades like Lophotrochozoa is less understood despite their remarkable ecological adaptations. Utilizing 238 lophotrochozoan genomes across eight phyla, we conducted a large-scale comparative genomics analysis to identify lineage-specifically expan… Show more

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