Evolving pathogens in the surgical intensive care unit: A 6-year experience

Starnes, Margaret J.; Brown, Carlos; Morales, I.; Hadjizacharia, Pantelis; Salim, Ali; Inaba, Kenji; Rhee, Peter; Δημητριάδης, Δημήτριος

doi:10.1016/j.jcrc.2008.02.007

Cited by 11 publications

(11 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Continuous changing of nosocomial pathogens has been previously reported (Starnes et al, 2008). Amsterdam et al (2010) Patients may be infected in the community and transfer these bacteria to hospitals, as happened for methicillin resistance S. aureus or vice versa (Song et al, 2011).…”

Section: Discussionmentioning

confidence: 98%

Comparative Study of Antibacterial Susceptibility Patterns of the Bacteria Isolated from Patients' Blood Samples over Two Periods

Japoni¹

2011

American Journal of Infectious Diseases

View full text Add to dashboard Cite

Problem statement: Due to continuous changes in the frequencies and antibacterial susceptibility patterns of nosocomial pathogens, periodical surveillance of these fluctuations could help the clinicians to treat hospitalized patients more efficiently whenever empirical therapies need to be considered. This study was conducted to compare the prevalence of the bacteria recovered from bloodstream samples by Bactec 9240, over the two periods of 2001-2004 and 2005-2008 and to evaluate their antibacterial susceptibility patterns. Approach: Totally, 3622 culture positive blood samples were analyzed over the periods. Antibacterial susceptibility patterns of the isolates were determined by standard disk diffusion (Kirby-Bauer) method. The data were compared in terms of quantity and quality of the pathogens and based on their distributions in three main wards. Results: Changes were observed in bacterial composition and frequencies of them, between the two periods. Compared with the first pried, increased frequencies of antibiotic resistant bacteria such as S. aureus, enterococci, acintobacter and pseudomonas were noticed in the second period. Most patients were admitted to pediatrics, followed by adults and neonates wards. Increased antibiotic resistance of the majority of the bacteria in the second period indicates the decreased efficacy of corresponding antibiotics. However, overall efficacy of some antibiotics such as ciprofloxacin and amikacin against Gram positive bacteria preserved. Conclusion: Trend of composition of the bacteria from first to second period could suggest the domination of antibiotic resistant bacteria over the sensitive ones. Appropriate strategies including strict control measures and rational prescription of the effective antibiotics may retard the trend accordingly. Vancomycin and imipenem were the most active antibiotics against Gram positive and negative bacteria. Combination of these two antibiotics is highly recommended for empirical therapy.

show abstract

Section: Discussionmentioning

confidence: 98%

Comparative Study of Antibacterial Susceptibility Patterns of the Bacteria Isolated from Patients' Blood Samples over Two Periods

Japoni¹

2011

American Journal of Infectious Diseases

View full text Add to dashboard Cite

show abstract

“…Yoğun bakım ünitesi gibi geniş spektrumlu antibiyotiklerin sık kullanıldığı yerlerde meydana gelen bakteriyemilerin en az % 10-20'sinin çoklu dirençli mikroorganizmalar tarafından oluşturulduğu bildirilmektedir (27) . Çoklu ilaç direnci günümüzde, beş ilaç grubundan (antipsödomonal sefalosporinler, karbapenemler, kinolonlar, aminoglikozidler ve β-laktam/β-laktamaz inhibitör kombinasyonları) birden fazlasına karşı duyarlılıkta azalma olarak tanımlanmaktadır (24) .…”

Section: Discussionunclassified

Evalution of Resistance to Various Antibiotics in Pseudomonas aeruginosa and Acinetobacter baumannii Strains Isolated from Blood Cultures of Intensive Care Patients

Uzun¹,

Güngör²,

Yurtsever³

et al. 2012

Ankem Derg

View full text Add to dashboard Cite

show abstract

“…The extensive use of broad-spectrum antibiotics can cause the selection of multidrug-resistant bacteria in the infections seen in ICU patients. Additionally, the general situaiton of ICU patients, the presence of underlying disease, the length of hospital stay, endogenous and resistant bacteria carriage of inpatients and application of more surgical procedures are some reasons of increasing number of resistant bacteria [18].…”

Section: Evaluation Of the Activities Of Antimicrobial Agents On Multmentioning

confidence: 99%

Evaluation of the Activities of Antimicrobial Agents on Multi-drug Resistant Gram Positive Bacteria Isolated from Intensive Care Units

Karameşe¹

2014

SOJ Microbiol Infect Dis

View full text Add to dashboard Cite

Evolving pathogens in the surgical intensive care unit: A 6-year experience

Cited by 11 publications

References 29 publications

Comparative Study of Antibacterial Susceptibility Patterns of the Bacteria Isolated from Patients' Blood Samples over Two Periods

Comparative Study of Antibacterial Susceptibility Patterns of the Bacteria Isolated from Patients' Blood Samples over Two Periods

Evalution of Resistance to Various Antibiotics in Pseudomonas aeruginosa and Acinetobacter baumannii Strains Isolated from Blood Cultures of Intensive Care Patients

Evaluation of the Activities of Antimicrobial Agents on Multi-drug Resistant Gram Positive Bacteria Isolated from Intensive Care Units

Contact Info

Product

Resources

About