2021
DOI: 10.1007/s11030-021-10256-w
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Evolving scenario of big data and Artificial Intelligence (AI) in drug discovery

Abstract: The accumulation of massive data in the plethora of Cheminformatics databases has made the role of big data and artificial intelligence (AI) indispensable in drug design. This has necessitated the development of newer algorithms and architectures to mine these databases and fulfil the specific needs of various drug discovery processes such as virtual drug screening, de novo molecule design and discovery in this big data era. The development of deep learning neural networks and their variants with the correspon… Show more

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Cited by 75 publications
(43 citation statements)
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References 186 publications
(138 reference statements)
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“…The S1 subunit represents the variable part of the protein, while the S2 subunit is much more conserved. The first 13 amino acid residues constituting the signal peptide (SP) of S1 are required to guide its transportation to its membrane destination [22]. The S1 subunit contains the N-terminal domain (NTD) (14-305) and RBD spanning 319-541 residues.…”
Section: Structural Organization Of S Proteinmentioning
confidence: 99%
“…The S1 subunit represents the variable part of the protein, while the S2 subunit is much more conserved. The first 13 amino acid residues constituting the signal peptide (SP) of S1 are required to guide its transportation to its membrane destination [22]. The S1 subunit contains the N-terminal domain (NTD) (14-305) and RBD spanning 319-541 residues.…”
Section: Structural Organization Of S Proteinmentioning
confidence: 99%
“…Finally, the use of them can grasp the learning status of students, enhance students' experience, and help achieve personalized teaching. Through facial recognition technology, teachers can view students' expressions in time and learn about students' knowledge points through student expressions [ 33 ]. After receiving information of students' performance, the teacher can adjust the teaching plan and methods in time to realize personalized teaching.…”
Section: The Role Of Them In Promoting Online Music Teachingmentioning
confidence: 99%
“…A second experiment followed, in order to add more complexity and possibilities to the experiment, we added a different noise factor to the experiment in a noisy environment. And it was experimented with the previous fixed energy threshold method and two-stage detection method [18]. e results are given in Table 3.…”
Section: Test Of Embedded English Speech Recognition System Inmentioning
confidence: 99%