Exacerbation aiguë des dilatations des bronches : imputabilité d’une infection à Corynebacterium striatum ?

Vandenbos, F.; Nicolai, Cecília Carmen de Araujo

doi:10.1016/j.rmr.2015.12.005

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…The literature search results are summarized in Figure 1 . The final analysis covered a total of 42 studies (35 case reports 1 , 2 , 12 - 44 and 7 case series 5 , 9 , 45 - 49 ) reporting 85 individual cases that met the inclusion criteria and did not present exclusion criteria. The median age of the subject with the reported C. striatum invasive infection was 65 (IQR 51, 72), with the oldest being 88 years old, while the youngest was 13 years old.…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial treatment of Corynebacterium striatum invasive infections: a systematic review

Milosavljević

Milosavljevic

Kočović

et al. 2021

Rev. Inst. Med. trop. S. Paulo

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The aim of this study was to establish an evidence-based guideline for the antibiotic treatment of Corynebacterium striatum infections. Several electronic databases were systematically searched for clinical trials, observational studies or individual cases on patients of any age and gender with systemic inflammatory response syndrome, harboring C. striatum isolated from body fluids or tissues in which it is not normally present. C. striatum had to be identified as the only causative agent of the invasive infection, and its isolation from blood, body fluids or tissues had to be confirmed by one of the more advanced diagnostic methods (biochemical methods, mass spectrometry and/or gene sequencing). This systematic review included 42 studies that analyzed 85 individual cases with various invasive infections caused by C. striatum . More than one isolate of C. striatum exhibited 100% susceptibility to vancomycin, linezolid, teicoplanin, piperacillin-tazobactam, amoxicillin-clavulanate and cefuroxime. On the other hand, some strains of this bacterium showed a high degree of resistance to fluoroquinolones, to the majority majority of β-lactams, aminoglycosides, macrolides, lincosamides and cotrimoxazole. Despite the antibiotic treatment, fatal outcomes were reported in almost 20% of the patients included in this study. Gene sequencing methods should be the gold standard for the identification of C. striatum , while MALDI-TOF and the Vitek system can be used as alternative methods. Vancomycin should be used as the antibiotic of choice for the treatment of C. striatum infections, in monotherapy or in combination with piperacillin-tazobactam. Alternatively, linezolid, teicoplanin or daptomycin may be used in severe infections, while amoxicillin-clavulanate may be used to treat mild infections caused by C. striatum .

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