Exacerbation of Multiple Sclerosis: A Clinical Paraclinical Paradox

Abstract

The purpose of our work was to find out the factors that determine the treatment tactics in the presence of signs of clinical and / or radiological exacerbation in patients with remitting multiple sclerosis. 104 patients were examined, 36.25 ± 9.81 years old. It has been established that in patients with shorter duration of the disease, the incidence of clinical (p <0.001) and radiological exacerbations (p <0.001) is higher. In patients who do not receive immunomodulatory therapy (p <0.05), there are signs of both clinical and radiological exacerbation. Patients with clinical exacerbations, regardless of the presence of active foci, receive treatment with methylprednisolone in almost 95% of cases. At the same time, in the case of radiological exacerbation, treatment with methylprednisolone is prescribed in only one third of the cases.