Examining the association between anthropometric parameters and telomere length and mortality risk

Chou

et al. 2018

Sci Rep

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Emerging evidences addressed an association between phosphate and muscle function. Because little attention was focused on this issue, the objective of our study was to explore the relationship of phosphate with muscle strength, dynapenia, and sarcopenia. From the National Health and Nutrition Examination Survey, a total of 7421 participants aged 20 years or older were included in our study with comprehensive examinations included anthropometric parameters, strength of the quadriceps muscle, and appendicular lean masses. Within the normal range of serum phosphate, we used quartile-based analyses to determine the potential relationships of serum phosphate with dynapenia, and sarcopenia through multivariate regression models. After adjusting for the pertinent variables, an inverse association between the serum phosphate quartiles and muscle strength was observed and the linear association was stronger than other anthropometric parameters. Notably, the significant association between phosphate and muscle strength was existed in >65 years old age group, not in 20–65 years old. The higher quartiles of phosphate had higher likelihood for predicting the presence of dynapenia rather than sarcopenia in entire population. Our study highlighted that higher quartiles of phosphate had significant association with lower muscle strength and higher risks for predicting the presence of dynapenia.

Section: Methodsmentioning

confidence: 99%

Exploring the Link between Serum Phosphate Levels and Low Muscle Strength, Dynapenia, and Sarcopenia

Chou

et al. 2018

Sci Rep

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“…The information including age, sex, race/ethnicity, personal habits, and medical history was derived from the NHANES database by self‐report. Furthermore, the biochemistry profiles, including MetS components were described in our previous articles …”

Section: Methodsmentioning

confidence: 99%

Peripheral fat distribution versus waist circumference for predicting mortality in metabolic syndrome

Diabetes Metabolism Res

et al. 2019

Objective: To elucidate whether the peripheral fat (PF)-combined definition of metabolic syndrome (MetS) would show a better predictive ability for cause-specific mortality than the common MetS. Methods: Data were derived from the National Health and Nutrition Examination Survey from 1999 through 2002. We investigated three types of MetS including waist circumference MetS (WCMetS), PFMetS, and PF-combined definition of MetS. The main outcome was to evaluate the predictive ability of the newly defined MetS for time to cause-specific mortality. The secondary outcomes were the relationships between the PF percentage and C-reactive protein (CRP) and homeostasis model assessment of insulin resistance (HOMA-IR) to clarify the gender discrepancy. Results: For cardiovascular mortality, the adjusted hazard ratios for WCMetS, PFMetS, and PF-combined definition MetS were 1.867, 1.742, and 2.117, respectively (all P < 0.001). A positive association between PF percentage and CRP in men and a negative correlation between PF percentage and HOMA-IR in women after adjustment for all variates were found. Conclusions:The PF-combined definition of MetS had a stronger predictive ability for all-cause and cardiovascular mortality than general MetS. Notably, the PF might have differential gender-specific health effects on cardiovascular events.

“…The anthropometric parameters were measured by standard procedures, which are found on the NHANES website. Detailed information about anthropometric measurements have been described in our earlier article . Additionally, the waist‐to‐thigh ratio (WTR) was the dimensionless ratio of the circumference of the waist to that of the thigh.…”

Section: Methodsmentioning

confidence: 99%

“…Detailed information about anthropometric measurements have been described in our earlier article. 11 Additionally, the waist-to-thigh ratio (WTR) was the dimensionless ratio of the circumference of the waist to that of the thigh. This was calculated as waist measurement divided by thigh measurement.…”

Section: Anthropometric Measurementsmentioning

confidence: 99%

Examining the association between vestibular function and lower extremity circumference in an aged population

Geriatrics Gerontology Int

et al. 2019

Aim To explore the association between vestibular dysfunction and specific anthropometric parameters. Methods The results from 2420 participants of the 1999–2004 National Health and Nutrition Examination Survey were included for the evaluation of vestibular dysfunction using the Romberg test of standing balance and anthropometric measurements, including waist circumference, thigh circumference, calf circumference (CC), waist‐to‐thigh ratio (WTR) and waist‐to‐calf ratio (WCR). Passing the balance test was defined as participants keeping their balance for 30 s while in the standing position with their eyes closed. Multivariable logistic regression models were the main statistical tools in the present study. Results The mean age of the participants was approximately 65 years, and half of the study participants were men. The full adjusted odds ratio of vestibular dysfunction for the CC, thigh circumference, WCR and WTR was 0.941 (95% confidence interval [CI], 0.894–0.992), 0.948 (95% CI 0.912–0.986), 1.856 (95% CI 1.087–3.170) and 2.516 (95% CI 1.235–5.126), respectively. Higher waist circumference along with lower thigh circumference and CC were observed in the participants in the higher WTR and WCR quartiles. Furthermore, a dose–response relationship between vestibular dysfunction and anthropometric ratios was detected. Discussion The present study showed that individuals with lower CC and thigh circumference or higher WCR and WTR exhibited higher odds of having vestibular dysfunction. Geriatr Gerontol Int 2019; 19: 622–627.