Excess serum Na level in rats administered with high doses of (−)-epigallocatechin gallate-casein nanoparticles prepared with sodium caseinate

Abstract

The 28-day oral toxicity test of 5.0 g per kg BW FD-EGCG-NPs on rats did not show any adverse effect. However, Na level in the serum of females and males treated with 10.0 g per kg BW FD-EGCG-NPs or FD-NPs significantly increased (P < 0.05).