Excessive caffeine intake inhibits steroidogenesis, folliculogenesis and disrupts utero-ovarian tissue histomorphology integrity in experimental rats, and precipitates polycystic ovary syndrome in Sprague-Dawley rats

Adelakun, Sunday Aderemi; Ogunlade, Babatunde; Aniah, Julius Akomaye; Akwu, Bala Peter; Afolabi, Maryam Oladoyin

doi:10.1016/j.focha.2024.100678

Food Chemistry Advances

2024

DOI: 10.1016/j.focha.2024.100678

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Excessive caffeine intake inhibits steroidogenesis, folliculogenesis and disrupts utero-ovarian tissue histomorphology integrity in experimental rats, and precipitates polycystic ovary syndrome in Sprague-Dawley rats

Sunday Aderemi Adelakun,

Babatunde Ogunlade,

Julius Akomaye Aniah

et al.

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2024

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Cited by 3 publications

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BCL-2 and BAX expression and germ cell apoptosis following the intervention of 1-isothiocyanato-4-methylsulfinylbutane in cisplatin-induced testicular toxicity and sperm DNA fragmentation in Sprague-Dawley rat

Adelakun,

Akintunde,

Ogunlade

et al. 2024

Aspects of Molecular Medicine

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BCL-2 and BAX expression and germ cell apoptosis following the intervention of 1-isothiocyanato-4-methylsulfinylbutane in cisplatin-induced testicular toxicity and sperm DNA fragmentation in Sprague-Dawley rat

Adelakun,

Akintunde,

Ogunlade

et al. 2024

Aspects of Molecular Medicine

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Neuroprotective mechanisms and ameliorative activities of quercetin in cisplatin-induced cerebellum neurotoxicity in rat models

Adelakun,

Ogunlade,

Aniah

et al. 2024

Brain Disorders

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Coffea plant (Caffeine): Examining its Impact on Physical and Mental Health

Alimyar,

Nahiz,

Monib

et al. 2024

ejmhr

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This research delves into the extensive use of caffeine across various consumables like foods, drinks, medications, and supplements. Caffeine's influence on the central nervous system renders it a popular substance globally. The study aims to elucidate how caffeine impacts health and overall well-being. It examines both the physical and mental repercussions of caffeine consumption, highlighting its advantages, risks, and individual differences in sensitivity. Moreover, the research investigates how caffeine affects diverse aspects such as sleep, mood, cognition, and physical performance, both positively and negatively. Notably, it also scrutinizes the association between caffeine intake and health conditions like heart disease, bone health, and mental well-being. The research promotes responsible caffeine consumption by advocating for moderation and understanding one's tolerance levels. It underscores the significance of comprehending caffeine's effects to enable informed decisions among consumers, healthcare providers, and policymakers. Emphasizing the prevalence of caffeine consumption, the study underscores the necessity of recognizing its impact on various bodily systems, including the cardiovascular, respiratory, endocrine, and neurological systems. While coffee, a common source of caffeine, offers health benefits, it's crucial to acknowledge caffeine as a chemical compound capable of influencing our nervous and other bodily systems. Excessive consumption of caffeine can pose detrimental effects on health. In essence, this research aims to raise awareness regarding the advantages and disadvantages associated with caffeine consumption. As the most widely consumed psychoactive substance globally, understanding caffeine's effects is imperative for maintaining overall well-being. Many individuals kickstart their day with coffee, unaware of both the positive and negative effects of caffeine.

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Excessive caffeine intake inhibits steroidogenesis, folliculogenesis and disrupts utero-ovarian tissue histomorphology integrity in experimental rats, and precipitates polycystic ovary syndrome in Sprague-Dawley rats

Cited by 3 publications

References 52 publications

BCL-2 and BAX expression and germ cell apoptosis following the intervention of 1-isothiocyanato-4-methylsulfinylbutane in cisplatin-induced testicular toxicity and sperm DNA fragmentation in Sprague-Dawley rat

BCL-2 and BAX expression and germ cell apoptosis following the intervention of 1-isothiocyanato-4-methylsulfinylbutane in cisplatin-induced testicular toxicity and sperm DNA fragmentation in Sprague-Dawley rat

Neuroprotective mechanisms and ameliorative activities of quercetin in cisplatin-induced cerebellum neurotoxicity in rat models

Coffea plant (Caffeine): Examining its Impact on Physical and Mental Health

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