Excessive dynamic airway collapse presenting as intractable cough: A case report

Aneeshkumar, Surendran; Thaha, Milan Malik; Varun, Sangeeta

doi:10.4103/lungindia.lungindia_89_18

Cited by 6 publications

(1 citation statement)

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“…The spirometry results in patients with TBM can exhibit various patterns, including a normal flow‐volume loop, notching of the flow‐volume loop, an oscillation pattern, and a biphasic pattern. 12 The biphasic pattern is marked by a sudden and significant drop in airflow at the beginning of expiration, followed by a plateau of low flow. 6 Our cases illustrate a distinctive biphasic pattern on the flow‐volume loop during expiration, which is considered one of the hallmarks of TBM.…”

Section: Discussionmentioning

confidence: 99%

Tracheobronchomalacia following allogeneic haematopoietic stem cell transplantation

Panpruang,

Eksombatchai,

Boonsarngsuk

2024

Respirology Case Reports

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Tracheobronchomalacia (TBM) occurs due to the weakening of cartilaginous part of the trachea, resulting in compromised airway function and leading to symptoms such as dyspnea, cough, and inability to clear secretions. Bronchiolitis obliterans syndrome (BOS) is the most prevalent late noninfectious pulmonary complication in patients who underwent allogeneic haematopoietic stem cell transplantation (HSCT). Therefore, patients experiencing progressive dyspnea and chronic cough after allogenic HSCT, with new obstructive pattern on pulmonary function test, are typically diagnosed with post‐transplant BOS. However, it is important to note that TBM can also manifest as an obstructive defect pattern on pulmonary function test. Tracheomalacia has been reported as a rare complication of allogenic stem cell transplantation. We present two patients who developed TBM following allogeneic HSCT and were initially treated for post‐transplant BOS but did not experience symptom improvement. However, after treatment with continuous positive airway pressure, their symptom subsided.

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Section: Discussionmentioning

confidence: 99%