Exercise for Leg Ulcers

Kirsner, Robert S.

doi:10.1001/jamadermatol.2018.2926

JAMA Dermatol

2018

DOI: 10.1001/jamadermatol.2018.2926

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Exercise for Leg Ulcers

Robert S. Kirsner

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Cited by 4 publications

(3 citation statements)

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“…To the Editor It was with great interest that I read the systematic review and meta-analysis by Jull et al (which analyzes our research group’s work, among that of others) as well as Kirsner’s related Editorial on the nature of venous leg ulcers (VLUs) . Together, they indicate a renewed interest in using exercise as an adjunct therapy to compression for people with VLUs.…”

mentioning

confidence: 99%

“…Although the pathophysiology of VLUs is elaborately discussed in the Editorial, I believe it is necessary (to better understand the potential therapeutic role of exercise) to discuss also the role of microvasculature in the condition. Indeed, our research group’s microcirculatory-focused studies on people with chronic venous insufficiency reveal that both the endothelium and the venous smooth muscle cells are affected in this clinical population.…”

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confidence: 99%

“…In conclusion, both the meta-analysis by Jull et al and the Editorial provide good service to all those working with people with this devastating, costly, and yet largely understudied condition. However, we still need large, multicenter trials that would explore the logistics, optimal exercise regimens, effectiveness, and cost-effectiveness of an exercise-based intervention that would ultimately be offered to this clinical population.…”

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confidence: 99%

See 2 more Smart Citations

The Role of Microcirculatory Dysfunction in the Pathophysiology and Treatment of Venous Leg Ulcers

Klonizakis

2019

JAMA Dermatol

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confidence: 99%

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confidence: 99%

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confidence: 99%

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The Role of Microcirculatory Dysfunction in the Pathophysiology and Treatment of Venous Leg Ulcers

Klonizakis

2019

JAMA Dermatol

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Leg ulceration in venous and arteriovenous insufficiency: assessment and management with compression therapy as part of a holistic wound‑healing strategy

Nair,

Mosti,

Atkin

et al. 2024

J Wound Care

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A Lower Leg Physical Activity Intervention for Individuals With Chronic Venous Leg Ulcers: Randomized Controlled Trial

Kelechi¹,

Prentice²,

Mueller³

et al. 2020

JMIR Mhealth Uhealth

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Background Individuals with venous leg ulcers (VLUs) suffer disproportionately with multiple chronic conditions, are often physically deconditioned, and demonstrate high levels of physical inactivity. Objective The primary objective of this randomized controlled trial was to establish the feasibility of a mobile health (mHealth) physical activity exercise app for individuals with VLUs to improve lower leg function. Methods In a 6-week study, adults with VLUs were recruited from 2 wound centers in South Carolina, United States, and enrolled if they were aged 18 years or older with impaired functional mobility and an ankle-brachial index between 0.8 and 1.3. Participants were randomized 1:1 to receive evidence-based, phased, nonexertive physical conditioning activities for lower leg function (FOOTFIT) or FOOTFIT+ with an added patient-provider communication feature. The mHealth Conditioning Activities for Lower Leg Function app also provided automated educational and motivational messages and user reports. Foot movement on the VLU-affected leg was tracked by a Bluetooth-enabled triaxial accelerometer. The study was guided by the Reach, Effectiveness, Adoption, Implementation, and Maintenance framework to assess the feasibility of reach, adherence, acceptability, implementation, and maintenance. Results A total of 24 patients were recruited, enrolled, and randomized in the study. Most patients reported difficulty following the protocol for exercising and using the accelerometer and mobile phone and did not use the provider contact feature. However, all patients were adherent to the 6-week exercise program more than 85% of the time for duration, whereas 33% (8/24) of patients adhered more than 85% for the frequency of performing the exercises. Across the three exercise levels, adherence did not differ between the two groups. Confidence limits around the difference in proportions ranged from −0.4 to 0.7. Providers in FOOTFIT+ were inconsistent in checking participant progress reports because of lack of time from competing work commitments. The technology became outdated quickly, making maintenance problematic. Participants said they would continue to exercise their foot and legs and liked being able to follow along with the demonstrations of each level of exercise provided through the app. Conclusions The findings of this study suggest that despite initial interest in using the app, several components of the program as originally designed had limited acceptability and feasibility. Future refinements should include the use of more modern technology including smaller wearable accelerometers, mobile phones or tablets with larger screens, an app designed with larger graphics, automated reporting for providers, and more engaging user features. Trial Registration ClinicalTrials.gov NTC02632695; https://clinicaltrials.gov/ct2/show/NCT02632695

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Exercise for Leg Ulcers

Cited by 4 publications

References 16 publications

The Role of Microcirculatory Dysfunction in the Pathophysiology and Treatment of Venous Leg Ulcers

The Role of Microcirculatory Dysfunction in the Pathophysiology and Treatment of Venous Leg Ulcers

Leg ulceration in venous and arteriovenous insufficiency: assessment and management with compression therapy as part of a holistic wound‑healing strategy

A Lower Leg Physical Activity Intervention for Individuals With Chronic Venous Leg Ulcers: Randomized Controlled Trial

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