This paper presents a new random weighting method to deal with the systematic error of the kinematic model for dynamic navigation. This method incorporates random weights in the kinematic model to control the systematic error of the kinematic model for improving the navigation accuracy. A theory of random weighting estimation is established, showing that 1) the random weighting estimation of the kinematic model's systematic error is unbiased and 2) the covariance matrix of the predicted state vector can be controlled by adjusting the covariance matrices of the predicted residual vector and estimated state vector to improve the accuracy of state prediction. Random weighting estimations are also constructed for the systematic error of the kinematic model as well as the covariance matrices of predicted residual vector, predicted state vector, and state noise vector. Experimental results demonstrate the effectiveness of the proposed random weighting method in resisting the Manuscript disturbances of the kinematic model noise for improving the accuracy of dynamic navigation. Yongmin Zhong is a senior lecturer within the School of Aerospace, Mechanical and Manufacturing Engineering, RMIT University, Melbourne, Australia. His research interests include virtual reality and haptics, soft tissue modelling and surgery simulation, robotics, mechatronics, optimum estimation and control, and integrated navigation system. Shesheng Gao is a professor at the School of Automatics, Northwestern Polytechnical University, Xi'an, China. His research interests include control theory and engineering, navigation, guidance and control, optimum estimation and control, integrated inertial navigation system, and information fusion.Weihui Wei is going for his Ph.D. degree at the School of Automatics, Northwestern Polytechnical University, Xi'an, China. His research interests include control theory and engineering, navigation, guidance and control, and information fusion.Chengfan Gu is an ARC DECRA fellow within the School of Aerospace, Mechanical and Manufacturing Engineering, RMIT University, Melbourne, Australia. Her current research activity includes computational modelling, micro/nano manufacturing, fatigue and bio/nano mechanics, and advanced materials characterization.