The performance of Transit Travel Time Reliability (TTR) influences service attractiveness, operating costs and system efficiency. Transit agencies have spent considerable effort on implementation of strategies related to advanced technologies capable of improving service reliability. Survey studies have shown that travelers tend to value a reduction in unreliability at least as important as a decrease in the average travel time. The increasing availability of data from automatic collection systems (e.g. automatic vehicle location, automatic fare collection, and etc.) provides opportunities in addressing transit TTR challenges. While most past studies estimate TTR for impact assessment of strategic and operational instruments, this research aims at developing generic models for TTR prediction that can fulfil different transit stakeholders' requirements (e.g. operators, unreliability causes identification; passengers, trip and departure planning). Three main issues are addressed, namely TTR quantification, TTR modelling and Travel Time Distribution (TTD) estimation. A unique integrated data warehouse was established for case studies of this research using different sources of data across six months of a year in Southeast Queensland area, Australia.For TTR quantification, a set of TTR measures from the perspective of passengers using the operational AVL data was proposed, considering different perceptions of TTR under different traffic states. The results show that the proposed measure can provide consistent TTR assessments with high-level of details, while the conventional TTR measures may give inconsistent assessments. For TTR modelling, the underlying determinants of travel time unreliability were identified and quantified on links of different road types using Seemingly Unrelated Regression Equations (SURE) estimation to account for the cross-equation correlations across regression models caused by unobserved heterogeneity. Targeted strategies can be introduced to improve TTR under different scenarios. For TTD estimation, a novel evaluation approach was developed to assess the most appropriate probability distributions for travel time components (link running times and stop dwell times). The Gaussian Mixture Models (GMM) distribution was assessed to be superior to its alternatives, in terms of fitting accuracy, robustness and explanatory power. The correlation structures of travel time components were explored using both a global and a local correlation measures. On these basis, a generalized Markov chain model was proposed to estimate the trip TTDs for arbitrary originationdestination pairs at arbitrary times given the individual link TTDs, by considering their spatiotemporal correlations. The proposed approach is generalizable and computationally more efficient, while it provides a comparable performance with reported models in literature.A major contribution of the research is the establishment of a generic TTD estimation methodology that can be applied for a comprehensive analysis and prediction of...