Experimental and numerical investigation on the transient vascular thermal response to multi‐pulse Nd:YAG laser

Abstract

For multi-pulse treatment, laser parameters are recommended as repetition rate of 10 Hz and pulse number of 10. The incident energy in each pulse should be strong enough to induce blood coagulation through seven or eight pulses and should be lower than the threshold of blood cavitation. Lasers Surg. Med. 49:852-865, 2017. © 2017 Wiley Periodicals, Inc.

Gold nanospheres enhanced photothermal therapy in a rat model

“…However, cavitation was observed immediately after laser irradiation when the concentration of PEG‐GNPs in blood was 2.5 mg/ml. Li et al reported that the formation of cavitation within blood vessels may cause hemorrhage, which should be avoided in clinic. Herein, the injection dosage of PEG‐GNPs should be less enough to prevent the side effect (i.e., formation of cavitation) in blood vessels after laser irradiation.…”

Successful Treatment of Reticular Blue Veins of the Lower Eyelid by Long-Pulse Nd: YAG – Case Report with 8-Year Follow-Up

“…In vitro experiment found that vessel constriction was due to the constriction of thrombus induced by laser irradiation. The theoretical investigation revealed that the mechanism for the effective reduction of energy density by multi-pulse Nd: YAG laser was due to enhanced light absorption of the blood with thrombus formation [ 9 ][ 10 ].…”

Relation between denaturation time measured by optical coherence reflectometry and thermal lesion depth during radiofrequency cardiac ablation: Feasibility numerical study

“…As computational models are a powerful, fast, and cheap tool to attain useful information on the electrical‐thermal processes associated with energy‐based therapies , this method was used to simulate the electric, thermal and tissue damage response of a two‐dimensional model of cardiac tissue subjected to RF ablation.…”