Experimental and theoretical study on the synthesis of gold nanoparticles using ceftriaxone as a stabilizing reagent for and its catalysis for dopamine

Abstract

Electrochemical synthesis of gold nanoparticles on the surface of glassy carbon electrode and preparation of GNPs in aqueous solution using ceftriaxone as an innocuous stabilizing reagent were proposed. The gold nanoparticles were characterized by scanning electron microscopy, transmission electron microscopy, infrared spectrometry, UV spectrophotometry, powder X-ray diffraction, and cyclic voltammetry. The catalysis of gold nanoparticles on the glassy carbon electrode for dopamine was demonstrated. The results indicate that the modified electrode has an excellent repeatability and reproducibility. The relationship between the molecular structure and the dispersion of GNPs on the surface of GCE as well as the catalysis of GNPs for dopamine was discussed.

Adsorbent Assisted in Situ Electrocatalysis: An Ultra-Sensitive Detection of As(III) in Water at Fe3O4 Nanosphere Densely Decorated with Au Nanoparticles

“…28,29 Although Au was known to be a poor catalyst in the bulk form, studies show that the nanosized Au particles exhibit excellent catalytic activity. 28,31 The Fe 3 O 4 -RTIL SPCE shows a higher sensitivity that is ascribed to the high adsorptivity 19 of Fe 3 O 4 microspheres toward As(III); this is consistent with our previous research. 27 Combining the catalysis of Au NPs and the adsorptivity of the Fe 3 O 4 microsphere, the sensitivity of Au@Fe 3 O 4 SPCE is better than that of Au and Fe 3 O 4 individually or even their sum.…”

“…Inspired by the excellent catalytic properties due to the small size of the Au nanoparticles − as well as the good adsorption ability of the Fe 3 O 4 nanosphere toward arsenic, we report here the concept of adsorbent-assisted in situ electrocatalysis for ultrasensitive detection of As­(III) on the Fe 3 O 4 nanosphere densely decorated with Au nanoparticles. The RTIL provides the necessary conduction pathways for electrons because of its good intrinsic conductivity, wide electrochemical windows, and high chemical and thermal stability. , The use of fabricated electrodes offered outstanding performance for As­(III) detection.…”

<p>Enhanced antibiotic activity of ampicillin conjugated to gold nanoparticles on PEGylated rosette nanotubes</p>

“…Furthermore, antibiotics could be conjugated to AuNPs in one simple step 10. Surface functionalization of AuNPs with antibiotics occurs because the drugs can coordinate to the surface of the AuNPs via their carboxylic acid, hydroxyl, thiol, or amine functional groups 11. The resulting functionalization imparts antibacterial properties to the AuNPs that consequently result in bacteria degradation and death 12…”

Antibiotic-Loaded Gold Nanoparticles: A Nano-Arsenal against ESBL Producer-Resistant Pathogens

“…The efficacies of these synthesized nanoparticles were further evaluated for their anticancer (against human breast cancer cells) and bactericidal effects (against ESBL-producing bacteria). It was found that Cef-AuNPs exhibited relatively low anticancer effects; however, conjugation of ceftriaxone on AuNPs restored the activity of ceftriaxone in otherwise resistant bacterial cells [ 66 ]. In addition, Pradeepa et al reported the biosynthesis of AuNPs with exopolysaccharide isolated from Lactobacillus plantarum , and their subsequent functionalization with ceftriaxone, ciprofloxacin, cefotaxime, and levofloxacin.…”