2022
DOI: 10.3390/w15010061
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Experimental Design and Bioassays as Tools to Investigate the Impact of Anodic Oxidation on Progestins Degradation

Abstract: The present study investigated the degradation of levonorgestrel (LNG) and gestodene (GES) through an anodic oxidation process mediated by active chlorine species. The independent variables [LNG]0 and [GES]0, current density (mA cm−2), and [NaCl]0 (mol L−1) were optimized through a response surface methodology (RSM) based on a four-level central composite design (CCD). Specific energy consumption allowed CCD-RSM analysis and optimization. The decay of progestins was followed to verify the kinetics of the anodi… Show more

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