Experimental dosimetry in conformal breast teletherapy compared with the planning system

Nogueira, Luciana Batista; Silva, Hugo Leonardo Lemos; Campos, Tânia Maria Mendonça

doi:10.1016/j.apradiso.2014.12.022

Cited by 9 publications

(18 citation statements)

References 14 publications

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“…Radiation therapy (RT) is one of the treatment methods that delivers a lethal dose on the tumor, sparing healthy tissues from the harmful effects of radiation [2,3]. The modalities often used in breast radiation therapy (breast-RT) involve megavoltage teletherapy, cobalt therapy, electron therapy and high-dose (HDR) brachytherapy by iridium-192 wires [4,5]. New equipment and technologies are in constant development, in order to decrease the dose received by the organs at risk (OARs) and to increase the precision of the dose in the target volume.…”

Section: Introductionmentioning

confidence: 99%

Reproduction of a left-breast 3DCRT field-in-field radiation therapy planning in an anthropomorphic and anthropometric phantom

Nogueira¹,

Geraldo²,

Barsanelli³

et al. 2019

Braz. J. Rad. Sci.

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The proposal of this study was to reproduce the dosimetry established by a treatment planning system (TPS) following a 3D conformational radiation therapy (3DCRT) protocol of two parallel-opposite fields applied to the left-breast in a thorax phantom, with the complementary use of the field-in-field technique. The computed tomography (CT) images of the thorax phantom were transferred to the XiO version-5 for the elaboration of the breast teletherapeutic planning with 2 Gy per day, in 25 fractions, with prescribed dose of 50 Gy. A set of ten EBT2 radiochromic films were irradiated at doses gradually. The values of RGB (Red, Green, Blue) of the films were obtained by scanning and data transformed in optical density (OD), whose values were used to construct the calibration curve. Radiochromic films were positioned outside and inside of the thorax phantom. After phantom radiation at the linear accelerator 6 MV Elekta Precise were measured the intensities of the films in RGB by software ImageJ, transformed in OD and converted in bidimensional dose distributions, applying the calibration curve. In addition, graphics and dose-volume histograms (DVH) were developed. The dose measurements in the glandular-TE in breast did not present statistically significant differences in relation to values at equivalent positions generated in the TPS. The organs at risk received doses below the reference values, according to TPS. It was possible to reproduce the dosimetry prescribed in TPS into the thorax phantom exposed to a breast conformational teletherapy. The use of the radiochromic films in dosimetry proves to be increasingly useful and shall become routine in radiotherapy services.

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Section: Introductionmentioning

confidence: 99%

Reproduction of a left-breast 3DCRT field-in-field radiation therapy planning in an anthropomorphic and anthropometric phantom

Nogueira¹,

Geraldo²,

Barsanelli³

et al. 2019

Braz. J. Rad. Sci.

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“…It is a RT requirement that the patient receives the entire prescribed dose in the target volume (PTV), holding the tolerable doses in the adjacent organs at risk (OARs). The International Commission of Radiation Unit and Measurements (ICRU) defines an OAR to be an uninvolved RT organ that, if receiving too much radiation dose, could be damaged and would compromise the success of the course of radiation therapy [13].…”

Section: Introductionmentioning

confidence: 99%

Experimental hypofractionated IMRT breast dosimetry in a thorax phantom

Pimenta¹,

Campos

Nogueira

2019

Braz. J. Rad. Sci.

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The present research proposal aimed to measure absorbed dose in a thorax phantom with synthetic breasts provided by an Intensity-Modulate Radiation Therapy (IMRT) protocol in an arbitrary RT center. As methods, a thorax simulator was prepared by the Ionizing Radiation Research Group (NRI) and radiochromic films were used for dose measurements. Tomographic images were taken at NRI phantom. Expositions were procedure in the Elektra 6MV LINAC. Hypofractionated regime was considered with a dose fraction of 2,7Gy in 16 fractions at the prescribed dose of 43.2 Gy at 95% of PTV. The dose comparison from the treatment planning system (TPS), Xio (Elekta) and from the experimental data was performed. The internal two-dimensional dose maps in the breast, at the skin on the left and contra-lateral breasts, heart and lungs. The measurements showed that the internal mean doses taken at the synthetic breast presented mean dose above the prescribed dose. Moreover, in general, doses to organs at risk (OARs) were within the Memorial Sloan Kettering Cancer Center (MSKCC) criteria. The non-full reproduction of the build-up region in the films had occurred due to the assymetrical positioning of the films in the inner breast, in the addition to their non-constant distance from the skin. Hot regions were present, may be due to the beam angulation chosen and the increase of MUs in the IMRT plane. As conclusions, the films can supply details and information that TPS does not provide. Assertiveness in clinical IMRT protocols can improve the prognosis and effectiveness of breast cancer treatment bring-ing possible clinical benefits.

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“…This object represents a breast in craniocaudal projection in position adjusted for mammographic examination. The final dimensions presented by phantom of developed compressed breast are of 4.5 cm of thickness, 15.0 cm of length and 6.0 cm of height [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Simulators of mammary pathologies enclosed on a breast phantom for image quality control in mammography

Souza

Nogueira

Campos³

2016

Scientia Plena

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This paper addresses the development of simulator of breast pathologies for image quality control in mammography. Simulators of neo density´s objects had been used for reproducing the breast pathologies. These objects had been adhered between two dental wax plates, inserted in an anthropomorphic and anthropometric compressed breast (AACB) phantom and submitted to radiological expositions. The AACB phantom is constituted of glandular, adipose and skin equivalent tissues, representing a fibro adipose breast with 50% of glandular and 50% adipose tissues. Radiographies of the AACB breast phantom were taken in the conventional and computerized systems. Two standard commercial breast phantoms referenced by the Brazilian College of Radiology and by the American College of Radiology were used as validation. After the expositions, qualitative image evaluation were carried through, identifying how many objects of the pathologies had been depicted, following the norms of quality control demanded by the Brazilian control agencies. The quality control measurements related to the pathology´s identifications, comparing with the standard breast phantoms, provided similar values. The simulating objects of mammary pathologies enclosed on the AACB phantom provide a suitable system for image quality control in mammography.

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Experimental dosimetry in conformal breast teletherapy compared with the planning system

Cited by 9 publications

References 14 publications

Reproduction of a left-breast 3DCRT field-in-field radiation therapy planning in an anthropomorphic and anthropometric phantom

Reproduction of a left-breast 3DCRT field-in-field radiation therapy planning in an anthropomorphic and anthropometric phantom

Experimental hypofractionated IMRT breast dosimetry in a thorax phantom

Simulators of mammary pathologies enclosed on a breast phantom for image quality control in mammography

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