Experimental evidence for the effect of ELF electric field on prostate cancer cell lines in-vitro

Abstract

Background The effect of extremely low frequency electric field on cancer cell proliferation is studied in-vitro. Methods Prostate cancer cell culture type Du-145 has been grown in the form of spheroids. It is shown that ELF with 50Hz frequency is effectively suppressing the growth of spheroids and finally reduces their size. Results It is observed that low voltage low frequency electric filed applied for at least 2 hours a day over one week can stop the growth or even reduce the volume of multi-cellular tumor spheroids significantly. No effect for the case of electric field presence in order of 10 -30 minutes per day has been observed.