Experimental measurement and correlation for solubility of piroxicam (a non-steroidal anti-inflammatory drugs (NSAIDs)) in supercritical carbon dioxide

Shojaee, Safar Ali; Rajaei, Hamid; Hezave, Ali Zeinolabedini; Lashkarbolooki, Mostafa; Esmaeilzadeh, Feridun

doi:10.1016/j.supflu.2013.03.015

Cited by 53 publications

(21 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Solvating power has direct relation with density, so when density increases, more solid can be solubilized. Thus, increases of pressure can increase the solvating power of supercritical carbon dioxide [36].…”

Section: Resultsmentioning

confidence: 99%

Solubility of Camphene and Caryophyllene Oxide in Subcritical and Supercritical Carbon Dioxide

Yeoh¹,

Choong²,

Adzahan³

et al. 2015

View full text Add to dashboard Cite

The solubility of camphene and caryophyllene oxide in subcritical and supercritical carbon dioxide were determined using dynamic off-line analysis method. Under subcritical condition, solubility of camphene and caryophyllene oxide were (1.738 to 18.118) • 10 -3 and (1.84 to 7.872) • 10 -3 respectively at 298.15 K with pressure varied from 50 to 70 bar. At 302.15 K and under same pressure variation, solubility of camphene and caryophyllene oxide were (1.918 to 18.76) • 10 -3 and (14 to 25.624) • 10 -3 respectively. Under supercritical condition, experiments were run from 80 bar to 250 bar. Solubility of camphene was ranged from (54.024 to 151.67) • 10 -3 at 308.15K and (17.552 to 65.487) • 10 -3 at 313.15 K; while solubility of caryophyllene oxide was ranged from (24.9 to 299.94) • 10 -3 at 308.15 K and (2.542 to 102.359) • 10 -3 at 318.15 K. These solubility data was correlated with three semi-empirical models which were Bartle, Chrastil and Mendez-Santiago-Teja model. Of these three models, Mendez-Santiago-Teja model showed excellent fitting with average absolute relative deviation kept below 2%.

show abstract

Section: Resultsmentioning

confidence: 99%

Solubility of Camphene and Caryophyllene Oxide in Subcritical and Supercritical Carbon Dioxide

Yeoh¹,

Choong²,

Adzahan³

et al. 2015

View full text Add to dashboard Cite

show abstract

“… P ref is a reference pressure value of 0.1 MPa, and ρ ref represents reference density; 700 kg/m 3 is used as this value usually lies within all sets of experimental temperature. The reason for ρ ref addition is to make sure that the a and b constants are less sensitive to the errors in the experimental solubility …”

Section: Methodsmentioning

confidence: 99%

Solubility correlation of gall (Quercus infectoria) extract in supercritical CO₂ using semi‐empirical equations

Nasir

Ismail

Machmudah

2017

Asia-Pacific J Chem Eng

View full text Add to dashboard Cite

The present work studied the solubilities of Quercus infectoria gall extract in supercritical carbon dioxide (SC‐CO2) system with the addition of methanol as polarity enhancer. Experimentally, the galls were extracted using SC‐CO2 at different operating pressures (20 to 30 MPa) and temperatures (50 to 70 °C). Six semi‐empirical equations (Chrastil, Adachi‐Lu, del Valle‐Aguilera, Sparks, Kumar‐Johnston and Bartle) were used to explain mathematically the solubility behaviour of the Q. infectoria gall extract. The results demonstrated that the extract solubility increases as pressure increases at fixed temperature, while at constant pressure, it increases with increasing temperature. Apparently, Bartle equation provides best correlation between experimental and calculated solubility data for gall extraction with high correlation coefficient, R2 (0.96), and small absolute average relative deviation (1.52%). © 2017 Curtin University of Technology and John Wiley & Sons, Ltd.

show abstract

“…(9), i belongs to CO 2 or solid solute. Therefore, β 11 -β 12 and β 21 -β 22 are the parameters belonging to solute and CO 2 , respectively. In this investigation, two differences exist in comparison with the work of Heidaryan and Jarrahian [18].…”

Section: Fugacity Of Components In the Fluid Phasementioning

confidence: 99%

“…However, cubic EOSs have a limited predictive capability. In addition, they are not accurate for complex systems such as the systems with associating or very heavy compounds [12]. In order to improve the accuracy of the results, an option is applying more complex equations of state based on the molecular theory of statistical mechanics (such as SAFT equation of state) or using more powerful mixing rules (such as Wong-Sandler mixing rule).…”

Section: Introductionmentioning

confidence: 99%

A New Simple Equation of State for Calculating Solubility of Solids in Supercritical Carbon Dioxide

Rostamian

Lotfollahi

2015

Period. Polytech. Chem. Eng.

View full text Add to dashboard Cite

show abstract

Experimental measurement and correlation for solubility of piroxicam (a non-steroidal anti-inflammatory drugs (NSAIDs)) in supercritical carbon dioxide

Cited by 53 publications

References 41 publications

Solubility of Camphene and Caryophyllene Oxide in Subcritical and Supercritical Carbon Dioxide

Solubility of Camphene and Caryophyllene Oxide in Subcritical and Supercritical Carbon Dioxide

Solubility correlation of gall (Quercus infectoria) extract in supercritical CO₂ using semi‐empirical equations

A New Simple Equation of State for Calculating Solubility of Solids in Supercritical Carbon Dioxide

Contact Info

Product

Resources

About

Experimental measurement and correlation for solubility of piroxicam (a non-steroidal anti-inflammatory drugs (NSAIDs)) in supercritical carbon dioxide

Cited by 53 publications

References 41 publications

Solubility of Camphene and Caryophyllene Oxide in Subcritical and Supercritical Carbon Dioxide

Solubility of Camphene and Caryophyllene Oxide in Subcritical and Supercritical Carbon Dioxide

Solubility correlation of gall (Quercus infectoria) extract in supercritical CO2 using semi‐empirical equations

A New Simple Equation of State for Calculating Solubility of Solids in Supercritical Carbon Dioxide

Contact Info

Product

Resources

About

Solubility correlation of gall (Quercus infectoria) extract in supercritical CO₂ using semi‐empirical equations