Experimental Pancreas Transplantation

Jj, Bergan; Ed, Teixeira

doi:10.1097/00007890-196707001-00022

Cited by 6 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our findings, which confirm a good insular function of pancreatic grafts, agree with previous studies on the subject [2,12,13,14,15,16,19,24,25,31,32]. Moreover, we have demonstrated that not only the B-cellular system but also the D-and extrainsular endocrine system are well preserved.…”

Section: Discussionsupporting

confidence: 92%

See 1 more Smart Citation

Islet Cytology in Experimental Pancreatic Transplantation

Bordi¹,

Peracchiá²,

Bobbio³

et al. 1970

Eur Surg Res

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 92%

“…From 1965 onward, several contributions concerning this subject [2,9,12,13,14,15,16,19,21,24,25,28,31,32] have remarkably increased our present knowledge of its technical, biological and functional aspects.…”

mentioning

confidence: 99%

Islet Cytology in Experimental Pancreatic Transplantation

Bordi¹,

Peracchiá²,

Bobbio³

et al. 1970

Eur Surg Res

View full text Add to dashboard Cite

“…Abnormal glucose homeostasis might be expected if the route of insulin secretion is altered. Some workers have reported hyperinsulinaemia and hypoglycaemia following heterotopic pancreatic transplantation and intraperitoneal isolated islet cell transplantation (Bergan & Teixeira, 1967;Sells, Calne, Hadjiyanakis & Marshall, 1972;Weber, Hardy, Lerner, Felig & Reemtsma, 1976a). This has been ascribed to the secretion of insulin into the systemic circulation and denervation of the transplanted tissue.…”

Section: Discussionmentioning

confidence: 99%

Neonatal Islet Cell Transplantation in the Diabetic Rat: Effect on Hepatic Enzyme Activity and Glucose Homeostasis

Y¹,

Smythe²,

Slater³

et al. 1977

Journal of Endocrinology

View full text Add to dashboard Cite

Intraperitoneal transplantation of collagenase-digested, isogeneic, neonatal rat pancreatic tissue successfully reversed streptozotocin-induced diabetes in 77% of recipients. The low serum immunoreactive insulin, hyperglycaemia, glycosuria and weight loss, characteristic of the diabetic animal, were corrected and the reduced activities of hepatic glucokinase and pyruvate kinase, and the low glycogen concentration of the liver of diabetic rats were restored to normal. Forty-three per cent of the successfully transplanted rats became normoglycaemic within 1 month of transplantation whereas 57% took from 1 to 6 months to achieve normoglycaemia and displayed a mild glucose intolerance when subjected to a glucose load. The rats which had not become normoglycaemic 6 months after transplantation showed some amelioration of the diabetic state, as shown by increased serum immunoreactive insulin and hepatic glycogen concentration and a slow weight gain compared with diabetic controls.

show abstract

Pancreas Transplantation in Man

Merkel¹

1971

Arch Surg

View full text Add to dashboard Cite

Experimental Pancreas Transplantation

Cited by 6 publications

References 0 publications

Islet Cytology in Experimental Pancreatic Transplantation

Islet Cytology in Experimental Pancreatic Transplantation

Neonatal Islet Cell Transplantation in the Diabetic Rat: Effect on Hepatic Enzyme Activity and Glucose Homeostasis

Pancreas Transplantation in Man

Contact Info

Product

Resources

About