This paper aims to review the engineering controls for indoor air quality (IAQ) from a systems design perspective. As a result of the review, we classify the literature content into three categories: (1) indoor air treatments, (2) dissemination control strategies, and (3) information technology. Indoor air treatments can be generally interpreted as the “cleaning” aspect, which covers ventilation and contaminant removal techniques. Dissemination control focuses on how contaminants generated in an indoor space can be transmitted, where four types of dissemination are classified. The category of information technology discusses IAQ sensors for monitoring, as well as the applications of the Internet of Things and IAQ data. Then, we further analyze the reviewed engineering controls by performing systems and functional analysis. Along with a discussion of IAQ functions, we suggest some systems design techniques, such as functional decoupling and design for flexibility/resilience, which are expected to promote more systems thinking in designing IAQ solutions.