Experimental study on effect of Plantago lanculata leaves extract on contaminated excisional wound healing in rabbits

Abstract

Objective: The experimental study was performed to assessment the influence of topical application of 10% of plantago lanceolata leaves extract (PLLE) in enhancement of contaminated excisional wound in 20 adult local breed rabbits. Methodology: Twenty adult local breed male rabbits were used in this experimental study. After animals anesthetized then twenty surgical excisional wound in diameter (2cm) were created on thoracic region (1wound\side). Rabbits were divided into control group in which wounds on right side were treated by irrigation with normal saline once \daily. Whereas, in treated group wounds on left side treated by topical application of 10% PLLE ointment (once\day). All wounds were dressing. The healing process was evaluated through macroscopic examination, wound contraction rate (WCR) and histopathological examination. Result: The presence study confirm there were significantly different at (P≤0.05) were registered between control and treated group along the time of study in which PMLE play accelerating role since it used.