Exploration of the Active Compounds of Moringa Oleifera Lam as Hiv-1 Reverse Transcriptase Inhibitor: A Network Pharmacology and Molecular Docking Approach
MELANDA FITRIANA,
ABDUL MUN’IM,
FIRDAYANI
et al.
Abstract:Objective: This study aims to predict the active compound of Moringa oleifera for the treatment of Human Immunodeficiency Virus (HIV), specifically targeting the HIV-1 reverse transcriptase (HIV-1 RT) enzyme using network pharmacology and molecular docking approach.
Methods: The active ingredients of M. oleifera, were screened from the Knapsack database. Subsequently, HIV-1 RT and its related target compounds were retrieved from the Genecard database. The analysis of common targets involved protein-protein int… Show more
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