As a hard and brittle material, KDP crystal is easily damaged by the irradiation of laser in a laser-driven inertial confinement fusion device due to various factors, which will also affect the quality of subsequent incident laser. Thus, the mechanism of laser-induced damage is essentially helpful for increasing the laser-induced damage threshold and the value of optical crystal elements. The intrinsic damage mechanism of crystal materials under laser irradiation of different pulse duration is reviewed in detail. The process from the initiation to finalization of laser-induced damage has been divided into three stages (i.e., energy deposition, damage initiation, and damage forming) to ensure the understanding of laser-induced damage mechanism. It is clear that defects have a great impact on damage under short-pulse laser irradiation. The burst damage accounts for the majority of whole damage morphology, while the melting pit are more likely to appear under high-fluence laser. The three stages of damage are complementary and the multi-physics coupling technology needs to be fully applied to ensure the intuitive prediction of damage thresholds for various initial forms of KDP crystals. The improved laser-induced damage threshold prediction can provide support for improving the resistance of materials to various types of laser-induced damage.