2019
DOI: 10.3390/jcm8112003
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Exploring a New Natural Treating Agent for Primary Hypertension: Recent Findings and Forthcoming Perspectives

Abstract: Primary hypertension describes abnormally-high systolic/diastolic blood pressure in a resting condition caused by various genetic or environmental risk factors. Remarkably, severe complications, such as ischemic cardiovascular disease, stroke, and chronic renal disease have led to primary hypertension becoming a huge burden for almost one-third of the total population. Medication is the major regimen for treating primary hypertension; however, recent medications may have adverse effects that attenuate energy l… Show more

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Cited by 11 publications
(4 citation statements)
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References 219 publications
(167 reference statements)
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“…144 We learn that Justin II had attempted to install the 'jilted' Anastasius' brother, Athanasius, as the miaphysite patriarch of Alexandria, all of which has been interpreted as a sign of the close relationship of Justin II and Sophia with the House of Theodora. 145 So, while Procopius offers us a distorted portrait of these marriages, the angst he conveys from some within the older nobility about this rising family is accurate. Procopius' fascination with these marriage alliances is a product of its troubled time.…”
Section: Discussionmentioning
confidence: 99%
“…144 We learn that Justin II had attempted to install the 'jilted' Anastasius' brother, Athanasius, as the miaphysite patriarch of Alexandria, all of which has been interpreted as a sign of the close relationship of Justin II and Sophia with the House of Theodora. 145 So, while Procopius offers us a distorted portrait of these marriages, the angst he conveys from some within the older nobility about this rising family is accurate. Procopius' fascination with these marriage alliances is a product of its troubled time.…”
Section: Discussionmentioning
confidence: 99%
“…Berdasarkan penelitian (Tika, 2021) hipertensi memiliki penyebab yang terbagi menjadi dua yaitu hipertensi primer dan hipertensi sekunder. Hipertensi primer merupakan penyabab yang masih belum diketahui penyebab pastinya, hipertensi primer paling sering ditemui dikalangan masyarakat, 90-95 % masyarakat terkena hipertensi primer (Lin et al, 2019). Hipertensi sekunder merupakan hipertensi yang jarang terjadi dimasyarakat, angka kejadian hipertensi sekunder jenis ini hanya mencapai 5-10% dari total penderita hipertensi (Puar et al, 2016).…”
Section: Gambar 5 Melakukan Pengisian Pretest Dan Posttestunclassified
“…This increases sodium reabsorption, triggering renin activation, which breaks down angiotensinogen to angiotensin I (AT-I), which is further broken down by an enzyme that converts angiotensin to angiotensin II (AT-II). AT-II triggers vasoconstriction of blood vessels 15 and also triggers the release of aldosterone from the adrenal glands which further increases the reabsorption of water and salt. 16 The RAAS system also affects the resistance of blood vessels by interfering with the function of nitric oxide (NO), which acts as a vasodilator and antagonist to AT-II function.…”
Section: Pathophysiology Of Hypertension and Its Relationships To Gut...mentioning
confidence: 99%