Exploring Chalcone Derivatives: Synthesis and Their Therapeutic Potential

Narwal, Sangeeta; Devi, Bhagwati; Dhanda, Tilak; Kumar, Sunil; Tahlan, Sumit

doi:10.1016/j.molstruc.2024.137554

Journal of Molecular Structure

2024

DOI: 10.1016/j.molstruc.2024.137554

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Exploring Chalcone Derivatives: Synthesis and Their Therapeutic Potential

Sangeeta Narwal,

Bhagwati Devi,

Tilak Dhanda

et al.

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Cited by 10 publications

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A Sustainable Approach for Palladium and Phosphane‐Free Sonogashira Type Cross‐Coupling of 2‐Chloroquinoline with Terminal Alkynes

Khalifa,

Patel

2024

ChemistrySelect

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An efficient and cost‐effective Cu (I) mediated protocol for the C(sp2)–C(sp) cross‐coupling of 3‐chalcone‐2‐chloroquinoline with terminal alkynes has been disclosed by optimizing a wide range of catalysts, ligands, base, and solvents. This approach conveniently assembles various alkynylated hybrids with excellent to moderate yields. Appropriate functional group tolerance and significant mechanistic pathway with mild reaction conditions well‐justified this synthetic transformation more sustainable towards the greener exploration.

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A Sustainable Approach for Palladium and Phosphane‐Free Sonogashira Type Cross‐Coupling of 2‐Chloroquinoline with Terminal Alkynes

Khalifa,

Patel

2024

ChemistrySelect

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Synergistic activity between conventional antifungals and chalcone-derived compound against dermatophyte fungi and Candida spp.

Maschio-Lima,

Lemes,

Marques

et al. 2024

Int Microbiol

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The Benzoxazole Heterocycle: A Comprehensive Review of the Most Recent Medicinal Chemistry Developments of Antiproliferative, Brain-Penetrant, and Anti-inflammatory Agents

Di Martino,

De Rosa

2024

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Exploring Chalcone Derivatives: Synthesis and Their Therapeutic Potential

Cited by 10 publications

References 61 publications

A Sustainable Approach for Palladium and Phosphane‐Free Sonogashira Type Cross‐Coupling of 2‐Chloroquinoline with Terminal Alkynes

A Sustainable Approach for Palladium and Phosphane‐Free Sonogashira Type Cross‐Coupling of 2‐Chloroquinoline with Terminal Alkynes

Synergistic activity between conventional antifungals and chalcone-derived compound against dermatophyte fungi and Candida spp.

The Benzoxazole Heterocycle: A Comprehensive Review of the Most Recent Medicinal Chemistry Developments of Antiproliferative, Brain-Penetrant, and Anti-inflammatory Agents

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