The concept of sustainable supply chain resilience has garnered significant attention in recent years, particularly in the context of global challenges such as climate change, geopolitical instability, and pandemics. This review delves into the conceptualization of sustainable supply chain resilience, focusing specifically on critical materials manufacturing in Africa as a catalyst for transformative change. Africa, endowed with abundant natural resources, has long been a focal point for discussions on economic development and industrialization. However, the continent faces numerous challenges, including limited infrastructure, political instability, and environmental degradation. Despite these challenges, there is a growing recognition of Africa's potential to emerge as a key player in global supply chains, particularly in the realm of critical materials manufacturing. Critical materials, essential components in various high-tech industries such as electronics, renewable energy, and aerospace, have become increasingly vital in today's interconnected world. Yet, the current global supply chain for critical materials is susceptible to disruptions, posing significant risks to industries and economies worldwide. Africa's rich endowment of critical materials presents an opportunity to diversify and strengthen the global supply chain, enhancing its resilience in the face of uncertainties. By strategically investing in critical materials manufacturing infrastructure and fostering sustainable practices, Africa can not only enhance its economic prosperity but also contribute to global sustainability efforts. Leveraging renewable energy sources, adopting eco-friendly production processes, and promoting responsible resource management are integral components of this endeavor. Furthermore, the development of sustainable supply chain resilience in Africa requires collaboration among various stakeholders, including governments, businesses, academia, and civil society. Policy interventions, technological innovation, and capacity-building initiatives are essential to create an enabling environment for sustainable development. Conceptualizing sustainable supply chain resilience in the context of critical materials manufacturing in Africa offers a pathway towards transformative change. By harnessing its natural resources responsibly and embracing sustainable practices, Africa can play a pivotal role in shaping a more resilient and sustainable global economy.