2024
DOI: 10.52601/bpr.2023.230028
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Exploring lysosomal biology: current approaches and methods

Qiuyuan Yin,
Chonglin Yang

Abstract: Lysosomes are the degradation centers and signaling hubs in the cell. Lysosomes undergo adaptation to maintain cell homeostasis in response to a wide variety of cues. Dysfunction of lysosomes leads to aging and severe diseases including lysosomal storage diseases (LSDs), neurodegenerative disorders, and cancer. To understand the complexity of lysosome biology, many research approaches and tools have been developed to investigate lysosomal functions and regulatory mechanisms in diverse experimental systems. Thi… Show more

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