2024
DOI: 10.1002/jcp.31495
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Exploring Metabolic Approaches for Epithelial Ovarian Cancer Therapy

Sangeeta Kumari,
Shraddha Gupta,
Aisha Jamil
et al.

Abstract: Epithelial ovarian cancer (EOC) has the highest mortality rate among malignant tumors of the female reproductive system and the lowest survival rate. This poor prognosis is due to the aggressive nature of EOC, its late‐stage diagnosis, and the tumor's ability to adapt to stressors through metabolic reprogramming. EOC cells sustain their rapid proliferation by altering the uptake, utilization, and regulation of carbohydrates, lipids, and amino acids. These metabolic changes support tumor growth and contribute t… Show more

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