Exploring Phytochemicals and Pharmacological Uses of Cordia Dichotoma (Indian Cherry): A Review

Abstract

The use of phytoconstituents single or combined with standard medicines has been utilized in cure of different diseases. Many plants of genus Cordia comprise of trees and shrubs are widely distributed in warmer regions and have been utilized in management of various diseases. Various phytoconstituents like flavonoids, alkaloids, terpenes, tannins, and glyceridess having different activities were screened and isolated from different parts of C. dichotoma. Various important Pharmacological properties including Antiulcer, Contraceptives, anti-inflammatory, anthelmintic, analgesic, anticancer, Antioxidant, antimicrobial, hepatoprotective, antidiabetic and others have been well documented for this plant. Therefore, we have briefly reviewed the various bioactivities of C. dichotoma to improve our knowledge on plant phytochemicals as therapeutic entities. The present review describes the various phytoconstituents and therapeutic potential of C. dichotoma that can be followed for future research on this plant for human health benefits.

Phytochemical fingerprinting and evaluation of in silico anti-thrombotic properties of Justicia adhatoda L. and Cordia dichotoma Frost.

“…Antimicrobial properties J. adathoda was demonstrated by Shinwari et al (2020). A number of in vitro and in vivo studies indicated that C. dichotoma contained quercetin that could improve cardiovascular functions (Prajapati et al, 2017). The results are shown in Figure 3.…”

Efficacy of chlorophyll a fluorescence kinetics and JIP test for early detection of leaf-gall disease in Cordia dichotoma

“…Cordia dichotoma mostly grows in trophic or subtropical environments and is native to India and Nepal. It is an ethnomedicinal plant from the family Boraginaceae that is mostly valued for its hepatoprotective, anti-diabetic, analgesic, anti-ulcer, anthelmintic, anti-inflammatory, aphrodisiac, immune-modulator, and diuretic properties (Hussain & Kakoti, 2013;Jamkhande & Barde, 2014;Rahman & Akhtar, 2016b;Prajapati et al, 2017;Bhaldar et al, 2021). Leaves, Fruits and seeds include sterols, pyrrolizidine alkaloids, apigenin, coumarins, taxifolin, flavonoids (kaempferol, quercetin, and isorhamnetin), saponins, terpenes, stearic, oleic, and linoleic acids, as well as coumarins, stearic acid, and apigenin (Ganjare et al, 2011;Jayaramudu et al, 2011;Jamkhande et al, 2013;Ragasa et al, 2015;Rahman & Akhtar, 2016a;Ali et al, 2017).…”

Antioxidant Potential of Cordia dichotoma: A Review

“…Many researchers reported various pharmacological applications of C. dichotoma such as Anti-ulcer 1 , Contraceptives 2 , anti-inflammatory 3,4,5,6 anthelmintic, analgesic, anticancer 4,7,8 , Antioxdant 8,9 , antimicrobial 10 , antifungal 10 , hepatoprotective 11 and diuretic purposes and for treating digestive system, respiratory, urogenital, cardiac, vascular and blood disorders. C. dichotoma is a promising source of natural antioxidants which possess remarkable therapeutic action as inflammatory activity and may serve as food ingredients 12,13,14,15 . Thus objectives of the present review are to provide an overview of the uses of C. dichotoma as herbal antioxidant.…”