Over the years, the exchange of goods and services between people has changed drastically, as new conditions have been added both in the sale and in the purchase to promote competitiveness between companies. For this reason, this article aimed to revolve around analyzing the aspects related to B2C trade during the Covid-19 pandemic and its effects on Colombian business. The methodology was quantitative and of documentary type. We reviewed information sources from different databases. We selected documents that responded to selection criteria associated with figures, data and analysis on electronic commerce, types of commerce, actors intervening between exchanges, innovation and commercial exchanges, most applied methodologies and tools, productivity improvements, and impact generated in the Colombian economy. The study results indicate that electronic commerce is a tool that has lost relevance for companies. But, the reality imposed by the pandemic favored its relaunch as part of the commercial activity that occurred during and after the pandemic. For this reason, this offers tremendous importance and support for acquiring products, goods and services between producers and consumers.