2024
DOI: 10.18632/aging.205971
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Exploring the mechanism by which Angelica sinensis improves haematopoietic function in aplastic anaemia

Zetao Chen,
Li Cheng,
Jing Zhang
et al.

Abstract: Angelica sinensis (AS) can improve the haematopoietic function, but the treatment mechanism is unknown. Transfusion dependency was estimated by Kaplan–Meier survival analyses and Cox proportional-hazard model in AS treated apalstic anemia (AA) patients. After that, the AA GEO database was analysed, the up differentially expressed genes (DEGs) of AA were combined with AS targets for the intersection of targets. After the AA mouse model was established, the effect of AS was confirmed by haematopoietic… Show more

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