2024
DOI: 10.1021/acsomega.4c02285
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Exploring the NRF2/HO-1 and NF-κB Pathways: Spirulina Nanoparticles as a Novel Approach to Combat Diabetic Nephropathy

Fayez Althobaiti,
Ehab S. Taher,
Lamya Ahmed Alkeridis
et al.

Abstract: Arthrospira platensis has been the subject of plentiful studies due to its purported health advantages; nevertheless, additional investigation is required to determine whether several chronic diseases may be treated or avoided with its nanoform. Therefore, we set out to examine A. platensis nanoparticles (SNPs) to protect against kidney impairment caused by Streptozotocin (STZ) in diabetic rats, precisely focusing on its effect and the cellular intracellular pathways involved. Male Wistar rats were assigned in… Show more

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Cited by 3 publications
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“…Examined samples were freshly prepared (5 mg dissolved in 10 mL of DDW). 31 Generally, the value of the zeta potential is related to stability, distribution proportion, and the charge of the NP surface in solution. A stability range around ±30 mV refers to moderate stability.…”
Section: Resultsmentioning
confidence: 99%
“…Examined samples were freshly prepared (5 mg dissolved in 10 mL of DDW). 31 Generally, the value of the zeta potential is related to stability, distribution proportion, and the charge of the NP surface in solution. A stability range around ±30 mV refers to moderate stability.…”
Section: Resultsmentioning
confidence: 99%