Exploring the potential application of dental pulp stem cells in neuroregenerative medicine

Sultan, Nessma; Scheven, Ben A.

doi:10.4103/1673-5374.322449

Cited by 1 publication

(1 citation statement)

References 12 publications

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“…In addition, Askari et al observed that oligodendrocyte progenitor cells derived from DPSCs have favorable therapeutic potential for treating sciatic nerve injury in a rodent model [ 129 ]. The neurotrophic growth factor secreted by DPSCs can be easily collected, purified, and stored, thus avoiding complications associated with stem cell treatment, such as unwanted proliferation and/or differentiation to unexpected cell types [ 132 , 133 ].…”

Section: Types Of Mesenchymal Stem Cells From the Oral Cavity (Dmsc I...mentioning

confidence: 99%

Adult Mesenchymal Stem Cells from Oral Cavity and Surrounding Areas: Types and Biomedical Applications

Cabaña-Muñoz,

Pelaz Fernández,

Parmigiani-Cabaña

et al. 2023

Pharmaceutics

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Adult mesenchymal stem cells are those obtained from the conformation of dental structures (DMSC), such as deciduous and permanent teeth and other surrounding tissues. Background: The self-renewal and differentiation capacities of these adult stem cells allow for great clinical potential. Because DMSC are cells of ectomesenchymal origin, they reveal a high capacity for complete regeneration of dental pulp, periodontal tissue, and other biomedical applications; their differentiation into other types of cells promotes repair in muscle tissue, cardiac, pancreatic, nervous, bone, cartilage, skin, and corneal tissues, among others, with a high predictability of success. Therefore, stem and progenitor cells, with their exosomes of dental origin and surrounding areas in the oral cavity due to their plasticity, are considered a fundamental pillar in medicine and regenerative dentistry. Tissue engineering (MSCs, scaffolds, and bioactive molecules) sustains and induces its multipotent and immunomodulatory effects. It is of vital importance to guarantee the safety and efficacy of the procedures designed for patients, and for this purpose, more clinical trials are needed to increase the efficacy of several pathologies. Conclusion: From a bioethical and transcendental anthropological point of view, the human person as a unique being facilitates better clinical and personalized therapy, given the higher prevalence of dental and chronic systemic diseases.

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Section: Types Of Mesenchymal Stem Cells From the Oral Cavity (Dmsc I...mentioning

confidence: 99%

Adult Mesenchymal Stem Cells from Oral Cavity and Surrounding Areas: Types and Biomedical Applications

Cabaña-Muñoz,

Pelaz Fernández,

Parmigiani-Cabaña

et al. 2023

Pharmaceutics

View full text Add to dashboard Cite

show abstract

Exploring the potential application of dental pulp stem cells in neuroregenerative medicine

Cited by 1 publication

References 12 publications

Adult Mesenchymal Stem Cells from Oral Cavity and Surrounding Areas: Types and Biomedical Applications

Adult Mesenchymal Stem Cells from Oral Cavity and Surrounding Areas: Types and Biomedical Applications

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