2024
DOI: 10.3389/fcell.2023.1297219
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Exploring the tumor micro-environment in primary and metastatic tumors of different ovarian cancer histotypes

Bingqing Xie,
Susan Olalekan,
Rebecca Back
et al.

Abstract: Ovarian cancer is a highly heterogeneous disease consisting of at least five different histological subtypes with varying clinical features, cells of origin, molecular composition, risk factors, and treatments. While most single-cell studies have focused on High grade serous ovarian cancer, a comprehensive landscape of the constituent cell types and their interactions within the tumor microenvironment are yet to be established in the different ovarian cancer histotypes. Further characterization of tumor progre… Show more

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