Exposure assessment in the Serbian population and occurrence of histamine and heavy metals in fish and seafood

Abstract

The aim of this study was to conduct a quantitative exposure assessment of fish-borne histamine, cadmium, mercury and arsenic in the Serbian adult population. The consumption survey of fish/fishery products was administered to 1 000 respondents during 2018. Determination of histamine content was performed on 974 fish; cadmium on 1 909, mercury on 1 911 and arsenic on 1 891 fish and seafood samples during five years (2014)(2015)(2016)(2017)(2018). Monte Carlo analysis was used to estimate the intake of histamine/ heavy metals from consumption of fish. The mean estimated daily intakes (EDIs) of fish-borne histamine, cadmium, mercury and arsenic by the Serbian adult population were 0.0274 mg kg −1 bw/day, 0.0347 μg kg −1 bw/day, 0.2426 μg kg −1 bw/day and 0.5576 μg kg −1 bw/day, respectively. Due to consumption of fish/seafood, 0.04% of the Serbian population are exposed to histamine, 0.05% to cadmium, 15.42% to mercury and 1.24% to arsenic levels over their respective thresholds.

Biomonitoring–Health Risk Nexus of Potentially Toxic Metals on Cerithidea obtusa: A Biomonitoring Study from Peninsular Malaysia

“…A significant impact of marine coastal pollution is metal-contaminated seafood, which has raised public attention due to its potential risks to human health [ 2 ]. Studies of PTMs in seafood have been increasing in the literature since the biomonitoring data are related to the human health risks of metal toxicity [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ]. In particular, many such biomonitoring studies with health risk assessments were reported from Pakistan [ 1 ], Thailand [ 2 ], Brazil [ 3 ], Serbia [ 4 ], China [ 5 , 19 , 21 , 24 ], Nigeria [ 6 , 25 ], Kuwait [ 8 ], Malaysia [ 9 , 26 ], Vietnam [ 11 ], Bosnia and Herzegovina [ 12 ], Romania [ 15 ], Serbia [ 16 ], Hungary [ 20 ] and Turkey [ 22 ].…”

“…Studies of PTMs in seafood have been increasing in the literature since the biomonitoring data are related to the human health risks of metal toxicity [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ]. In particular, many such biomonitoring studies with health risk assessments were reported from Pakistan [ 1 ], Thailand [ 2 ], Brazil [ 3 ], Serbia [ 4 ], China [ 5 , 19 , 21 , 24 ], Nigeria [ 6 , 25 ], Kuwait [ 8 ], Malaysia [ 9 , 26 ], Vietnam [ 11 ], Bosnia and Herzegovina [ 12 ], Romania [ 15 ], Serbia [ 16 ], Hungary [ 20 ] and Turkey [ 22 ]. The six PTMs that were investigated in the present study were Cd, Cu, Fe, Ni, Pb and Zn because they are common anthropogenic metals and could potentially cause human health risks [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 ,…”

“…In particular, many such biomonitoring studies with health risk assessments were reported from Pakistan [ 1 ], Thailand [ 2 ], Brazil [ 3 ], Serbia [ 4 ], China [ 5 , 19 , 21 , 24 ], Nigeria [ 6 , 25 ], Kuwait [ 8 ], Malaysia [ 9 , 26 ], Vietnam [ 11 ], Bosnia and Herzegovina [ 12 ], Romania [ 15 ], Serbia [ 16 ], Hungary [ 20 ] and Turkey [ 22 ]. The six PTMs that were investigated in the present study were Cd, Cu, Fe, Ni, Pb and Zn because they are common anthropogenic metals and could potentially cause human health risks [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. All the studies reported [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ,...…”

“…The six PTMs that were investigated in the present study were Cd, Cu, Fe, Ni, Pb and Zn because they are common anthropogenic metals and could potentially cause human health risks [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. All the studies reported [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ] did indicate that the ultimate rationale for using the molluscs when biomonitoring PTMs in coastal waters is that they are consumed extensively in some areas of the world and hence pose a risk to human health [ 26 ]. Thus, this was followed by human health risk assessments of the monitored PTMs in seafood […”

Assessment of health risks associated with heavy metal concentration in seafood from North-Western Croatia

“…Due to their potential to bioaccumulate, the concentration of heavy metals in organisms located at higher trophic levels can reach concentrations that may be harmful to human health. Thus, the consumption of seafood in general and fish in particular is the main exposure route to heavy metals 9 – 11 . Exposure to heavy metals including lead (Pb), cadmium (Cd) and mercury (Hg) can lead to a number of adverse health effects, including a compromised renal and hepatic function 12 , teratogenic effects 13 – 15 , and cognitive impairments 16 , 17 .…”