Exposure to acute electromagnetic radiation of mobile phone exposure range alters transiently skin homeostasis of a model of pigmented reconstructed epidermis

Simon, Dagmar; Daubos, Alexia; Pain, Catherine; Fitoussi, R.; Vié, Katell; Taı̈eb, Alain; Benetti, L. D.; Cario‐André, Muriel

doi:10.1111/j.1468-2494.2012.00746.x

Cited by 13 publications

(6 citation statements)

References 28 publications

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“…These findings were obtained by testing three signal types (CW, GSM basic and GSM talk) and by employing several tests to measure apoptosis. Simon et al (2013), exposed reconstruct epidermis from human skin biopsy to 900 MHz, GSM basic for 6 h at an SAR level of 2 W/kg. After RF exposure, growth medium was replaced with fresh medium, and reconstructed epidermis was incubated at 37 °C and 5% CO2 for 2, 6, 18 or 24 h. Results indicated no significant variation of p53 and caspase 3 in exposed samples compared to sham exposed ones.…”

Section: Non Genotoxic Effectsmentioning

confidence: 99%

Ecological study on the penetration of induction heating cookers and birth outcomes in Japan

et al. 2020

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About the Scientific CommitteesThree independent non-food Scientific Committees provide the Commission with the scientific advice it needs when preparing policy and proposals relating to consumer safety, public health and the environment. The Committees also draw the Commission's attention to the new or emerging problems which may pose an actual or potential threat.They are: the Scientific Committee on Consumer Safety (SCCS), the Scientific Committee on Health and Environmental Risks (SCHER) and the Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR).In addition, the Commission relies upon the work of the European Food Safety Authority (EFSA), the European Medicines Agency (EMA), the European Centre for Disease prevention and Control (ECDC) and the European Chemicals Agency (ECHA). SCENIHRThis Committee deals with questions related to emerging or newly identified health and environmental risks and on broad, complex or multidisciplinary issues requiring a comprehensive assessment of risks to consumer safety or public health and related issues not covered by other Community risk assessment bodies. Examples of potential areas of activity include potential risks associated with interaction of risk factors, synergic effects, cumulative effects, antimicrobial resistance, new technologies such as nanotechnologies, medical devices including those incorporating substances of animal and/or human origin, tissue engineering, blood products, fertility reduction, cancer of endocrine organs, physical hazards such as noise and electromagnetic fields (from mobile phones, transmitters and electronically controlled home environments), and methodologies for assessing new risks. It may also be invited to address risks related to public health determinants and non-transmissible diseases.

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Section: Non Genotoxic Effectsmentioning

confidence: 99%

Ecological study on the penetration of induction heating cookers and birth outcomes in Japan

et al. 2020

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“…But, some investigator reported that the electromagnetic radiation (900 MHz, SAR 2 mWg -1 ) did not affect to skin at the point of cellular stress and pigmentation [10]. But electromagnetic radiation and electromagnetic field are different physical area, therefore, the results of each stimulations could not the same.…”

Section: Introductionmentioning

confidence: 99%

Pigmentation effect of electromagnetic fields at various intensities to melanocytes

Cho

Kim

Kang³

et al. 2016

Tissue Eng Regen Med

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Melanogenesis is the biological process that results in the synthesis of skin pigment of melanin and it has various functions in living systems and is synthesized by the melanosome within the melanocytes. A variety of physical treatments are used to promote melanin production in the melanocytes for pigmentation control. The purpose of this study was to evaluate the intensity-dependent effect of extremely low-frequency electromagnetic fields (ELF-EMFs) on melanogenesis by melanocytes in vitro. Melanocytes were exposed to ELF-EMFs at a frequency of 50 Hz and at intensities in the range of 0.5-20 G over 4 days. The results of lactate dehydrogenase assay showed that there were no significant differences between cells exposed to 0.5 G or 2 G groups and the controls. The melanin contents increased 1.2-1.5-fold in cells exposed to ELF-EMFs and tyrosinase activity increased 1.3-fold in cells exposed to ELF-EMFs, relative to the controls. Also, exposure to ELF-EMFs was associated with activation in cyclic-AMP response element binding protein and microphthalmia-associated transcription factor (MITF) was up-regulated. Up-regulation of MITF induces the expression of melanogenesis-related markers, such as tyrosinase, tyrosinase-related protein (TRP)-1, TRP-2. In conclusion, the present study showed that the exposure to ELF-EMFs at low intensities can stimulate melanogenesis in melanocyte, and these results may be used to a therapeutic devices for inducing repigmentation in vitiligo patients.

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“…It has been reported that non-thermal effects of EMR could induce lipid peroxidation in human erythrocytes [ 7 ], oxidative damage in rabbits and rat’s brains [ 8 , 9 , 10 ], and alteration of epidermal homeostasis [ 11 ]. EMR exposure may also induce changes in the endocrine system [ 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Correlation of Blood Oxidative Stress Parameters to Indoor Radiofrequency Radiation: A Cross Sectional Study in Jordan

Akkam

Al-Taani

Ayasreh

et al. 2020

IJERPH

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Background: Electromagnetic pollution is a general health concern worldwide, as cell phone towers are ubiquitous and are located adjacent to or on the roof of schools, and hospitals. However, the health risks are still inconclusive. This cross-sectional study evaluated the potential effect of electromagnetic radiation generated from various resources including cell phone towers on blood glutathione S transferase activity (e-GST) and total antioxidant activity of the Jordanian population. Methods: The power density of three districts in the city of Irbid, Jordan was mapped to generate “outside the houses” and “inside the houses” maps. The effect of categorical variables (gender, using a cell phone, presence of Wi-Fi modem, previous exposure to medical imaging) and continuous variables (distance from the base station, the elevation of the house, the duration of stay in the house, power density outside houses, power density inside houses) on e-GST and total antioxidant activity were investigated. Results: The EMR generated outside the houses—including cell phone towers—did not reach inside the houses at the same power and had no significant influence on e-GST activity. The EMR inside the house, which primarily came from internal resources, has a significant effect on e-GST activity. The duration of stay inside the house, the use of cell phones, and the presence of a Wi-Fi modem had a proportional effect on e-GST activity. The total antioxidant activity was statistically equal between the tested and control groups. Conclusions: Several factors such as building materials restricted the penetration of EMR reaching inside the houses. EMR generated inside rather than outside the houses had a proportional effect on e-GST. The differences in e-GST were compensated successfully by other antioxidant mechanisms. Further research is needed to identify other possible sources of antioxidants, and to evaluate long-term effects and genetic polymorphism.

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Exposure to acute electromagnetic radiation of mobile phone exposure range alters transiently skin homeostasis of a model of pigmented reconstructed epidermis

Cited by 13 publications

References 28 publications

Ecological study on the penetration of induction heating cookers and birth outcomes in Japan

Ecological study on the penetration of induction heating cookers and birth outcomes in Japan

Pigmentation effect of electromagnetic fields at various intensities to melanocytes

Correlation of Blood Oxidative Stress Parameters to Indoor Radiofrequency Radiation: A Cross Sectional Study in Jordan

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