Exposure to an enriched environment modulates the synaptic vesicle cycle in a mouse spinal cord injury model
Jeehyun Yoo,
Ji Cheol Shin,
Kil-Byung Lim
et al.
Abstract:Spinal cord injury (SCI) leads to motor and sensory impairment below the site of injury, thereby necessitating rehabilitation. An enriched environment (EE) increases social interaction and locomotor activity in a mouse model, similar to human rehabilitation. However, the impact of EE on presynaptic plasticity in gene expression levels remains unclear. Hence, this study aimed to investigate the therapeutic potential of EE in an SCI mouse model. Mice with spinal cord contusion were divided into two groups: those… Show more
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