Exposure to particulate matter (PM2.5) and prevalence of diabetes mellitus in Indonesia

Suryadhi, Made Ayu Hitapretiwi; Suryadhi, Putu Ayu Rhamani; Abudureyimu, Kawuli; Ruma, I Made Winarsa; Calliope, Akintije Simba; Wirawan, Dewa Nyoman; Yorifuji, Takashi

doi:10.1016/j.envint.2020.105603

Cited by 20 publications

(6 citation statements)

References 27 publications

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“…In our study, participants aged 45 and older were more vulnerable to type 2 diabetes under long-term exposure to PM 2.5 , PM 10 , and NO 2 . Similar conclusions can be found in numerous previous studies, suggesting stronger positive associations between air pollution and T2DM among middle-aged and elderly population ( Chen et al, 2016 ; Eze et al, 2014 ; Honda et al, 2017 ; Liu et al, 2019 ; Suryadhi et al, 2020 ). This may be owing to age-related decline of physiological function, physical reserves, immune system, stress response and so on ( Collins, 1987 ; Sacks et al, 2011 ; Vasto et al, 2007 ).…”

Section: Discussionsupporting

confidence: 91%

How long-term air pollution and its metal constituents affect type 2 diabetes mellitus prevalence? Results from Wuhan Chronic Disease Cohort

Chen

Qin

Liu

et al. 2022

Environmental Research

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Section: Discussionsupporting

confidence: 91%

How long-term air pollution and its metal constituents affect type 2 diabetes mellitus prevalence? Results from Wuhan Chronic Disease Cohort

Chen

Qin

Liu

et al. 2022

Environmental Research

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“…Each study included one or more kinds of air pollution, and the outcome of each study was the disease prevalence or incidence. [34] Cohort [35] Cohort [36] Cross-sectional Jabbari F, et al (2020) [37] Cohort study Municipal [38] Cross [39] Cross [43] Cohort [45] study municipalities in all 33 provinces in Indonesia 2013 1.14) prevalence been diagnosed with diabetes mellitus by a doctor? "…”

Section: Resultsmentioning

confidence: 99%

Association between Air Pollution and Type 2 Diabetes Mellitus in Developing Countries: A Systematic Review and Meta-Analysis

Chen¹,

Zhang²,

Deng³

et al. 2022

Chinese Medical Sciences Journal

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Objective In recent years, many studies have reported that air pollution is a risk factor for type 2 diabetes mellitus (T2DM). The aim of this systematic review and meta-analysis is to summarize the evidence about the association between exposure to air pollution andT2DM in developing countries. MethodsThe databases, including PubMed, EMBASE and Web of Science, were systematically searched for studies published up to 31 March 2022. Studies about the association between air pollution and T2DM prevalence or incidence in developing countries were included. The odds ratio (OR) was used as effect estimate.We synthesized the included studies in meta-analyses. ResultsWe included 8 cross-sectional studies and 8 cohort studies, all conducted in developing countries. Meta-analyses of 8 studies on PM 2.5 (particulate matter ≤ 2.5 μm in diameter) showed that the overall effect estimate of T2DM prevalence upon exposure to PM 2.5 was 1.12 (95% CI: 1.07, 1.17).

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“…Although there is a lack of information on the hypothalamic consequences of pollutant exposure in humans, epidemiological studies indicate that air pollution increases the risk of metabolic disease, which may be worsened by poor lifestyle choices such as lack of exercise, alcohol consumption, and obesity (118). Observational studies in humans have linked exposures to various pollutants including PM 2.5 and ozone with higher rates of T2DM in populations across the globe (119)(120)(121)(122)(123). Healthy mothers living near busy streets at preconception had increased fasting blood glucose levels, suggesting that air pollution exposure contributes to metabolic imbalance (124).…”

Section: Mechanisms Linking Hypothalamic Metabolic Programming and Po...mentioning

confidence: 99%

Prenatal Pollutant Exposures and Hypothalamic Development: Early Life Disruption of Metabolic Programming

et al. 2022

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Environmental contaminants in ambient air pollution pose a serious risk to long-term metabolic health. Strong evidence shows that prenatal exposure to pollutants can significantly increase the risk of Type II Diabetes (T2DM) in children and all ethnicities, even without the prevalence of obesity. The central nervous system (CNS) is critical in regulating whole-body metabolism. Within the CNS, the hypothalamus lies at the intersection of the neuroendocrine and autonomic systems and is primarily responsible for the regulation of energy homeostasis and satiety signals. The hypothalamus is particularly sensitive to insults during early neurodevelopmental periods and may be susceptible to alterations in the formation of neural metabolic circuitry. Although the precise molecular mechanism is not yet defined, alterations in hypothalamic developmental circuits may represent a leading cause of impaired metabolic programming. In this review, we present the current knowledge on the links between prenatal pollutant exposure and the hypothalamic programming of metabolism.

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Exposure to particulate matter (PM2.5) and prevalence of diabetes mellitus in Indonesia

Cited by 20 publications

References 27 publications

How long-term air pollution and its metal constituents affect type 2 diabetes mellitus prevalence? Results from Wuhan Chronic Disease Cohort

How long-term air pollution and its metal constituents affect type 2 diabetes mellitus prevalence? Results from Wuhan Chronic Disease Cohort

Association between Air Pollution and Type 2 Diabetes Mellitus in Developing Countries: A Systematic Review and Meta-Analysis

Prenatal Pollutant Exposures and Hypothalamic Development: Early Life Disruption of Metabolic Programming

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