2024
DOI: 10.2147/jhc.s483861
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Expression and Targeted Application of Claudins Family in Hepatobiliary and Pancreatic Diseases

Fangqian Du,
Yuwei Xie,
Shengze Wu
et al.

Abstract: Hepatobiliary and pancreatic diseases are becoming increasingly common worldwide and associated cancers are prone to recurrence and metastasis. For a more accurate treatment, new therapeutic strategies are urgently needed. The claudins (CLDN) family comprises a class of membrane proteins that are the main components of tight junctions, and are essential for forming intercellular barriers and maintaining cellular polarity. In mammals, the claudin family contains at least 27 transmembrane proteins and plays a ma… Show more

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