2020
DOI: 10.5603/dk.2020.0037
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Expression of Notch 2 and ABCC8 genes in patients with type 2 diabetes mellitus and their association with diabetic kidney disease

Abstract: Background. The incidence of type 2 diabetes mellitus (T2DM) has increased over the past years and early identification and management of its complications especially diabetic kidney disease (DKD) is of great importance. T2DM and DKD are of multifactorial etio logy with contribution of genetic and environmental factors. We aimed to study the expression of ABCC8 and Notch 2 genes in patients with T2DM and to find their association with DKD. Methods. The present work was carried on 80 patients with T2DM (40 with… Show more

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