2023
DOI: 10.1590/1806-9282.20230360
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Expression of sirtuin 2 and 7 in placenta accreta spectrum

Abstract: SUMMARY OBJECTIVE: This study aimed to investigate the expression levels of sirtuin 2 and sirtuin 7 in the placenta accreta spectrum to reveal their role in its pathogenesis. METHODS: A total of 30 placenta accreta spectrum, 20 placenta previa, and 30 controls were experienced. The sirtuin 2 and sirtuin 7 expression levels in the placentas of these groups were determined by Western blot. sirtuin 2 and sirtuin 7 serum levels in the maternal and fetal cord bl… Show more

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Cited by 2 publications
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“…Recently, there have been more and more publications on the activity of sirtuins in placental tissue in normal and complicated pregnancies. This applies in particular to SIRT1 in placental vascular endothelial cells and trophoblast cells [8,[183][184][185][186]. Directly involved in many key intra-cellular reactions, SIRT1 builds up the connection between epigenetics and metabolism at the placental level [187].…”
Section: Discussionmentioning
confidence: 99%
“…Recently, there have been more and more publications on the activity of sirtuins in placental tissue in normal and complicated pregnancies. This applies in particular to SIRT1 in placental vascular endothelial cells and trophoblast cells [8,[183][184][185][186]. Directly involved in many key intra-cellular reactions, SIRT1 builds up the connection between epigenetics and metabolism at the placental level [187].…”
Section: Discussionmentioning
confidence: 99%