2024
DOI: 10.3390/diseases12030051
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Expression Patterns of GATA3 in Classical Hodgkin Lymphoma: A Clinico-Pathological Study

Alexandra Papoudou-Bai,
Epameinondas Koumpis,
Georgia Karpathiou
et al.

Abstract: GATA3 is a transcription factor involved in T-cell maturation and has been previously shown to be aberrantly overexpressed in malignant Hodgkin and Reed–Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL). However, the immunophenotypes of the cell types expressing GATA3 have not been precisely characterized so far in cHL tissues. In this single-center retrospective cohort study we analyzed the expression patterns of GATA3 alone and in combination with B, T, NK or macrophage-associated markers in 73 cases… Show more

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