2012
DOI: 10.1155/2012/283560
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Expression Profiling of a Heterogeneous Population of ncRNAs Employing a Mixed DNA/LNA Microarray

Abstract: Mammalian transcriptomes mainly consist of non protein coding RNAs. These ncRNAs play various roles in all cells and are involved in multiple regulation pathways. More recently, ncRNAs have also been described as valuable diagnostic tools. While RNA-seq approaches progressively replace microarray-based technologies for high-throughput expression profiling, they are still not routinely used in diagnostic. Microarrays, on the other hand, are more widely used for diagnostic profiling, especially for very small nc… Show more

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“…Les puces dédiées à l'analyse des seuls microARN (miARN) sont en revanche utilisées en routine dans de nombreux laboratoires. Ces puces sont généra-lement composées d'oligonucléotides de type LNA (locked nucleic acids) (Figure 1) [7]. Tm : température moyenne.…”
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“…Les puces dédiées à l'analyse des seuls microARN (miARN) sont en revanche utilisées en routine dans de nombreux laboratoires. Ces puces sont généra-lement composées d'oligonucléotides de type LNA (locked nucleic acids) (Figure 1) [7]. Tm : température moyenne.…”
unclassified