Extended-Duration Thromboprophylaxis With Enoxaparin After Arthroscopic Surgery of the Anterior Cruciate Ligament: A Prospective, Randomized, Placebo-Controlled Study

Marlovits, Stefan; Striessnig, Gabriele; Schuster, Raimund; Stocker, Roland; Luxl, Monika; Trattnig, Siegfried; Vécsei, V.

doi:10.1016/j.arthro.2007.02.001

Cited by 88 publications

(100 citation statements)

References 24 publications

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“…5,12,23,24 Nonetheless, the 2012 American College of Chest Physicians guidelines recommend no routine use of thromboprophylaxis in knee arthroscopy patients other than early mobilization (grade 2B). For patients with "additional thromboembolic risk factors or following a complicated procedure," however, thromboprophylaxis with LMWH is recommended (grade 1B).…”

Section: Discussionmentioning

confidence: 97%

“…Currently, the reported incidence of VTEs without thromboprophylaxis after knee arthroscopy ranges from 0.6% to 18%, depending on the diagnostic method used. [2][3][4][5][6] Most published studies have included relatively small numbers of patients and provided few risk factors for these events, [7][8][9] making it difficult to create definitive guidelines for thromboprophylaxis in knee arthroscopy patients. Nonetheless, there are classic risk factors for the development of VTEs described in the literature.…”

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confidence: 99%

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Incidence and Risk Factor Analysis of Symptomatic Venous Thromboembolism After Knee Arthroscopy

Krych

Sousa

Morgan

et al. 2015

Arthroscopy: The Journal of Arthroscopic & Related Surgery

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Section: Discussionmentioning

confidence: 97%

mentioning

confidence: 99%

Incidence and Risk Factor Analysis of Symptomatic Venous Thromboembolism After Knee Arthroscopy

Krych

Sousa

Morgan

et al. 2015

Arthroscopy: The Journal of Arthroscopic & Related Surgery

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“…This may or may not be attributed to our approach of all patients [31,32,54]. In a randomized trial evaluating the rate of VTE with the use of LMWH after ACL reconstruction, Marlovits et al [28] had a reduced rate of VTE in the treatment group of 2.8% compared with 41.2% in the placebo group, but it is important to note that all their patients were screened for VTE. Despite the nature of the multiligamentous knee reconstruction being more complex and time-consuming than a standard arthroscopic ACL reconstruction, rates of symptomatic VTE appear similar between multiligamentous knee reconstruction with routine use of thromboprophylaxis and ACL reconstruction groups, which generally were managed without it.…”

Section: Discussionmentioning

confidence: 99%

Low Frequency of Symptomatic Venous Thromboembolism After Multiligamentous Knee Reconstruction With Thromboprophylaxis

Born¹,

Engasser

King

et al. 2014

Clinical Orthopaedics &Amp; Related Research

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Background Reconstruction of the multiligament-injured knee often involves extended surgical and tourniquet use times and often is performed in patients who have sustained concomitant fractures as well as vascular injuries, all of which would appear to predispose the patient to the potentially serious complications of deep vein thrombosis and perhaps pulmonary embolism, yet little is known about the frequency of venous thromboembolic (VTE) events after multiligamentous knee reconstruction. Questions/purposes The purposes of this study were to (1) determine the frequency of symptomatic VTE after multiligamentous knee reconstruction at a single institution; and (2) to determine associated risk factors for VTE in these patients. Methods The records of 134 (63% of the 213 consented individuals in our longitudinal database) patients who underwent primary (129 [96%]) or revision (five [4%]) multiligamentous knee reconstruction at a single institution between 1992 and 2013 were retrospectively reviewed. With two patients undergoing procedures bilaterally, this resulted in a total of 136 multiligamentous knee reconstructions. VTE for which clinical symptoms were evident and confirmed by imaging within 3 months after the reconstructive procedure was noted. Pre-and perioperative data were collected with respect to demographics, associated injuries, medical history, smoking status, and surgical data. Standard rehabilitation and thromboprophylaxis protocols were used in all patients. Results Three cases of symptomatic VTE (three deep vein thromboses) occurred after the 136 reconstructions (2%; 95% confidence interval, 0.53%-7.3%). Two of the three patients were obese and the remaining patient smoked and abused alcohol. However, as a result of a low frequency of VTE, no risk factors could be identified in this series. Conclusions Symptomatic VTE occurred in 2% of multiligamentous knee reconstructions at our institution while receiving thromboprophylaxis. This is similar to rates documented after anterior cruciate ligament reconstruction without thromboprophylaxis. Further multicenter research is required to identify the true frequency of and risk factors for developing VTE in patients undergoing multiligamentous knee reconstruction after knee dislocation. Level of Evidence Level III, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

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“…Zur Dauer der Prophylaxe ist zu sagen, dass nur wenige vergleichenden Studien mit unterschiedlicher Dauer durchgeführt wurden [45]. Die deutsche S 3-Leitlinie gibt eine konkrete Empfehlung für die Dauer mit einem Empfehlungsgrad mittlerer Stärke ("sollte"), die unten aufgeführt ist.…”

Section: Studienübersicht: Doak Und Ktepunclassified

Thromboseprophylaxe in der muskuloskelettalen Chirurgie

Pabinger‐Fasching¹,

Eichinger-Hasenauer²,

Grohs

et al. 2014

Wien Klin Wochenschr

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Extended-Duration Thromboprophylaxis With Enoxaparin After Arthroscopic Surgery of the Anterior Cruciate Ligament: A Prospective, Randomized, Placebo-Controlled Study

Cited by 88 publications

References 24 publications

Incidence and Risk Factor Analysis of Symptomatic Venous Thromboembolism After Knee Arthroscopy

Incidence and Risk Factor Analysis of Symptomatic Venous Thromboembolism After Knee Arthroscopy

Low Frequency of Symptomatic Venous Thromboembolism After Multiligamentous Knee Reconstruction With Thromboprophylaxis

Thromboseprophylaxe in der muskuloskelettalen Chirurgie

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