Extensive fixed drug eruption due to lamotrigine

Positive patch test in hypersensitivity to lamotrigine

“…Patch testing is a well‐known method for diagnostic confirmation in patients with generalized maculopapular Type IV hypersensitivity reactions (3). A positive patch test with lamotrigine has been described before (4) in a patient with a fixed drug eruption. As far as we know, this is the first case of anticonvulsant hypersensitivity syndrome from lamotrigine confirmed by a positive patch test.…”

Extensive Fixed Drug Eruption Secondary to Vancomycin

“…In particular, the lips, genitalia, and sacral area have an increased incidence of developing these lesions, although they can appear on any part of the body (8). While uncommon, extensive and generalized fixed drug eruptions have been reported related to various causative agents (9–14). The treatment of fixed drug eruption involves discontinuation of the offending drug, resulting in healing of the lesions, usually within 2 weeks.…”

Abstract

“…1 ; Poirot A. 3 ; De Blay F. 3 ; Geny B. Nevertheless, few studies investigated at Mt roles in peripheral immune cells.…”